Hebei University of Chinese Medicine, Shijiazhuang, China.
Henan University of Chinese Medicine, Zhengzhou, China.
Medicine (Baltimore). 2023 Dec 29;102(52):e36794. doi: 10.1097/MD.0000000000036794.
Autism spectrum disorder (ASD) has evolved from a narrow and rare childhood-onset disorder to a widely publicized and researched lifelong disease recognized as common and significantly heterogeneous. Researchers have suggested that gastrointestinal symptoms in ASD may be a manifestation of an underlying inflammatory process. However, there is a lack of bibliometric analysis of ASD and gut microbiota in children. Accordingly, this study conducts a bibliometric analysis of ASD and gut microbiota in children from 2000 to 2023, explores the current status and cutting-edge trends in the field of ASD and gut microbiota in children, and identifies new directions for future research. The literature on ASD and gut microbiota in children was screened using the Web of Science Core Collection from 2000 to 2023. Annual publications, countries, institutions, authors, journals, keywords, and references were visualized and analyzed using CiteSpace 5.8. R3 and VOSviewer1.6.18. This study included 1071 publications. Since the beginning of 2011, the overall number of articles shows an upward trend. The most productive country and institution are the United States and the University of California system, respectively. The most frequently cited author is Kang Dae-Wook, with 790 citations, who has contributed significantly to this field. Timothy Dinan is the most prolific author, with 34 articles. The journal with the most published articles on this topic is Nutrients, whereas PLOS One is the most cited journal. The most used keyword is "gut microbiota," and the reference for the highest outbreak intensity is Hsiao. The research hotspots and trends predicted in this study provide a reference for further in-depth research in this field.
自闭症谱系障碍（ASD）已从一种狭隘且罕见的儿童期发病障碍演变为一种广为人知且研究深入的终身疾病，被认为是常见且具有显著异质性的疾病。研究人员提出，自闭症谱系障碍患者的胃肠道症状可能是潜在炎症过程的一种表现。然而，目前缺乏针对儿童自闭症谱系障碍和肠道微生物群的文献计量分析。因此，本研究对 2000 年至 2023 年儿童自闭症谱系障碍和肠道微生物群进行了文献计量分析，探讨了儿童自闭症谱系障碍和肠道微生物群领域的现状和前沿趋势，并确定了未来研究的新方向。使用 Web of Science Core Collection 从 2000 年至 2023 年筛选了儿童自闭症谱系障碍和肠道微生物群的文献。使用 CiteSpace 5.8. R3 和 VOSviewer1.6.18 可视化和分析了年度出版物、国家、机构、作者、期刊、关键词和参考文献。本研究共纳入 1071 篇文献。自 2011 年初以来，总体文章数量呈上升趋势。最具生产力的国家和机构分别是美国和加利福尼亚大学系统。被引频次最高的作者是 Kang Dae-Wook，有 790 次引用，他对该领域做出了重大贡献。Timothy Dinan 是发文量最多的作者，有 34 篇文章。发表该主题文章最多的期刊是《Nutrients》，而被引频次最高的期刊是《PLOS One》。使用最多的关键词是“gut microbiota”，引用强度最高的参考文献是 Hsiao。本研究预测的研究热点和趋势为该领域的进一步深入研究提供了参考。
