探索 B 族维生素：饮食多样性、微生物合成与人类健康。

Navigating the B vitamins: Dietary diversity, microbial synthesis, and human health.

机构信息

State Key Laboratory of Genetic Engineering, Fudan Microbiome Center, School of Life Sciences, and Human Phenome Institute, Fudan University, Shanghai 200433, China.

State Key Laboratory of Genetic Engineering, Fudan Microbiome Center, School of Life Sciences, and Human Phenome Institute, Fudan University, Shanghai 200433, China; College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.

出版信息

Cell Host Microbe. 2024 Jan 10;32(1):12-18. doi: 10.1016/j.chom.2023.12.004.

DOI:10.1016/j.chom.2023.12.004

PMID:38211561

Abstract

B vitamins are intricately involved in various physiological processes vital for health. Their significance is complicated by the heterogeneous landscape of B vitamin distribution in diets and the contributions of the gut microbiota. Here, we delve into the impact of these factors on B vitamins and introduce strategies, with a focus on microbiota-based therapeutic options, to enhance their availability for improved well-being. Additionally, we provide an ecological and evolutionary perspective on the importance of B vitamins to human-microbiota interactions. In the dynamic realms of nutrition and microbiome science, these essential micronutrients continue to play a fundamental role in our understanding of disease development.

摘要

B 族维生素在各种对健康至关重要的生理过程中都有着错综复杂的关系。其重要性因饮食中 B 族维生素分布的异质性以及肠道微生物群的贡献而变得复杂。在这里，我们深入探讨了这些因素对 B 族维生素的影响，并介绍了一些策略，重点是基于微生物群的治疗选择，以提高其可用性，从而改善健康。此外，我们还从生态和进化的角度探讨了 B 族维生素对人类-微生物群相互作用的重要性。在营养和微生物组科学的动态领域，这些必需的微量营养素在我们对疾病发展的理解中继续发挥着基础性作用。