维生素C与普通感冒：审视相关证据。

Ascorbic acid and the common cold: reviewing the evidence.

作者信息

Coulehan J L

出版信息

Postgrad Med. 1979 Sep;66(3):153-5, 157-8, 160. doi: 10.1080/00325481.1979.11715253.

DOI:10.1080/00325481.1979.11715253

Abstract

Large-scale clinical trials of the effect of vitamin C on the common cold conducted since Pauling's pronouncement on its efficacy in 1970 have produced conflicting results. Benefits shown have been modest, and positive findings have not been reproducible. Reported benefits probably are due to statistical artifact, minor vitamin-induced physiologic changes, the placebo effect, or a combination of these.

摘要

自1970年鲍林宣称维生素C对普通感冒有效以来，针对其效果开展的大规模临床试验结果相互矛盾。所显示的益处并不显著，而且阳性结果无法重复出现。报告的益处可能归因于统计假象、维生素引起的轻微生理变化、安慰剂效应或这些因素的综合作用。