完成了来自 Miscanthus sp. 的新 betaflexivirus 芒草病毒 M 的全序列和基因组特征描述。
Complete sequence and genome characterization of miscanthus virus M, a new betaflexivirus from Miscanthus sp.
机构信息
USDA-ARS National Germplasm Resources Laboratory, Beltsville, MD, USA.
USDA-ARS Molecular Plant Pathology Laboratory, Beltsville, MD, USA.
出版信息
Arch Virol. 2024 Jan 12;169(2):27. doi: 10.1007/s00705-024-05966-z.
A novel betaflexivirus, tentatively named "miscanthus virus M" (MiVM), was isolated from Miscanthus sp. The complete genome of MiVM is 7,388 nt in length (excluding the poly(A) tail). It contains five open reading frames and has a genome organization similar to those of members of the families Alphaflexiviridae and Betaflexiviridae (subfamily Quinvirinae). The amino acid sequences of both the replicase and coat protein shared less than 45% identity with the corresponding sequences of members of either family. Phylogenetic analysis confirmed that MiVM belongs to the family Betaflexiviridae and subfamily Quinvirinae but it was too distantly related to be included in any currently recognized genus in this family. We therefore propose that miscanthus virus M represents a new species and a new genus in the family Betaflexiviridae.
一种新的贝塔卷曲病毒，暂定名为“芒草病毒 M”（MiVM），从芒草属植物中分离出来。MiVM 的完整基因组长 7388 个核苷酸（不包括 poly(A)尾）。它包含五个开放阅读框，基因组组织与阿尔法卷曲病毒科和贝塔卷曲病毒科（ quinvirinae 亚科）的成员相似。复制酶和外壳蛋白的氨基酸序列与任一家族成员的相应序列的同一性均小于 45%。系统发育分析证实，MiVM 属于贝塔卷曲病毒科和 quinvirinae 亚科，但与该科目前已知的任何属都没有密切的关系。因此，我们建议芒草病毒 M 代表贝塔卷曲病毒科的一个新种和新属。
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