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老年人慢性苯二氮䓬类药物使用:在入住急性老年病房的患者中的流行率、适应证和治疗调整。

Chronic benzodiazepine usage among older people: prevalence, indications, and treatment modifications in patients admitted to an acute geriatric unit.

机构信息

Servicio de Geriatría, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.

出版信息

Eur Geriatr Med. 2024 Apr;15(2):539-543. doi: 10.1007/s41999-023-00918-3. Epub 2024 Jan 12.

Abstract

AIM

To investigate the prevalence and indications of benzodiazepines (BZD) usage among patients admitted to an acute geriatric unit and assess changes in prescriptions.

METHODS

BZD indications were documented reviewing clinical records, with appropriateness assessed based on the STOPP-START criteria. Changes in BZD prescriptions were recorded at discharge and 3 months later.

RESULTS

Among the 366 patients included (mean age: 92.8 years, 68% females), 91 (24.9%) were on BZD upon admission, being inappropriate in 93.4%. At discharge, BZD discontinuation was observed in 40.7% and dose reduction initiated in 57.4%. Among patients discharged without prescriptions, 10.8% resumed their use at 3 months. Of those discharged with BZD tapering, 74.1% were still on them 3 months later.

CONCLUSIONS

The majority of patients employing BZD lacked a medical indication. Admission to a geriatric ward resulted in successful discontinuation or dose reduction for most patients but was not maintained in the outpatient setting.

摘要

目的

调查入住老年急性病科患者使用苯二氮䓬类药物(BZD)的流行情况和适应证,并评估处方的变化。

方法

通过查阅病历记录 BZD 的适应证,根据 STOPP-START 标准评估其适宜性。在出院时和 3 个月后记录 BZD 处方的变化。

结果

在纳入的 366 例患者中(平均年龄:92.8 岁,68%为女性),91 例(24.9%)患者入院时正在使用 BZD,其中 93.4%的患者使用不当。出院时,40.7%的患者停止使用 BZD,57.4%的患者开始减少剂量。在出院时未开处方的患者中,有 10.8%在 3 个月时恢复使用。在接受 BZD 逐渐减量的患者中,74.1%的患者在 3 个月后仍在使用。

结论

大多数使用 BZD 的患者缺乏医学适应证。入住老年病房后,大多数患者成功地停止或减少了 BZD 的使用,但在门诊环境中并未维持。

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