Milne J A
Postgrad Med J. 1979 May;55(643):318-24. doi: 10.1136/pgmj.55.643.318.
The respiratory response to pregnancy appears to be largely mediated by the action of progesterone and, perhaps to a lesser extent, oestrogens, at least in the first and second trimesters. The mechanical effects of the gravid uterus cause relatively little change in pulmonary mechanics, although finer changes in airways function require further investigation. Dyspnoea during pregnancy is also probably hormone-mediated but the exact temporal relationship between hormone status, functional change and the development of symptoms is not yet clearly defined.
妊娠期间的呼吸反应似乎很大程度上是由孕酮的作用介导的,在妊娠前三个月和第二个三个月,雌激素的作用可能较小。妊娠子宫的机械作用对肺力学的影响相对较小,尽管气道功能的细微变化需要进一步研究。孕期呼吸困难也可能是由激素介导的,但激素状态、功能变化和症状发展之间的确切时间关系尚未明确界定。