Department of Surgery, Henry Ford Health, Detroit, MI, USA.
Clin Exp Metastasis. 2024 Aug;41(4):375-380. doi: 10.1007/s10585-023-10262-2. Epub 2024 Jan 13.
Axillary management in patients with breast cancer is in a constant state of evolution. To provide appropriate treatment recommendations, we must understand the historical implications and the current indications for nodal staging as well as the clinical implications of nodal metastases. As we move away from maximal axillary surgical intervention that was previously the mainstay of breast cancer management, future research efforts will focus on targeted therapies based on tumor biology and identifying oncologically safe methods to de-escalate our management strategies.
乳腺癌患者的腋窝管理正处于不断发展的状态。为了提供适当的治疗建议，我们必须了解淋巴结分期的历史意义和当前指征，以及淋巴结转移的临床意义。随着我们逐渐摒弃以前乳腺癌治疗的主要手段——最大限度的腋窝手术干预，未来的研究工作将集中在基于肿瘤生物学的靶向治疗上，并确定降低我们管理策略风险的肿瘤学上安全的方法。
