网格蛋白轻链包含脑特异性插入序列以及与中间丝的同源区域。
Clathrin light chains contain brain-specific insertion sequences and a region of homology with intermediate filaments.
作者信息
Jackson A P, Seow H F, Holmes N, Drickamer K, Parham P
出版信息
Nature. 1987;326(6109):154-9. doi: 10.1038/326154a0.
DOI:10.1038/326154a0
PMID:3821891
Abstract
The primary structures of four bovine clathrin light chains have been determined. Light chains LCa and LCb are homologous proteins encoded by different genes. In the brain the messenger RNA from these genes undergoes differential splicing to yield proteins having centrally inserted brain-specific sequences. A potentially alpha-helical region of the clathrin light chains shows homology with intermediate filament proteins.
摘要
已确定了四种牛源网格蛋白轻链的一级结构。轻链LCa和LCb是由不同基因编码的同源蛋白。在大脑中，来自这些基因的信使核糖核酸经过可变剪接，产生具有在中央插入的脑特异性序列的蛋白质。网格蛋白轻链的一个潜在α螺旋区域与中间丝蛋白具有同源性。
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