Bonnekoh Linda M, Fellmeth Ruth, Dübbers Angelika, Oesingmann-Weirich Sandra, Fernholz Judith, Omran Heymut, Romer Georg
Klinik für Kinder- und Jugendpsychiatrie, -psychosomatik und-psychotherapie, Universitätsklinikum Münster, Deutschland.
Klinik für Kinder- und Jugendmedizin, Allgemeine Pädiatrie, Universitätsklinikum Münster, Deutschland.
Z Kinder Jugendpsychiatr Psychother. 2024 Nov;52(6):354-360. doi: 10.1024/1422-4917/a000964. Epub 2024 Jan 15.
Case Report of a 14-Year-Old Girl with Addison's Disease Under Initial Presumptive Diagnosis of Anorexia Nervosa: Confusingly Similar and Yet so Different? Primary adrenal insufficiency (Addison's disease) is a rare differential diagnosis of anorexia nervosa. This case report presents important differential diagnostic aspects. We prepared a case report of a 14-year-old female patient according to the CARE guidelines, taking the patient's and the child's parents' view into consideration. The diagnosis of primary adrenocortical insufficiency was reached using specific laboratory diagnostics approximately 9 months after the onset of symptoms, including sudden body weight loss. Significant differential diagnostic aspects were the absence of a body schema disorder and skin hyperpigmentation prominent in the physical examination. The patient experienced a high psychosocial burden because of the unclear diagnosis over 9 months. The diagnosis and substitution therapy with hydrocortisone led to a rapid improvement of the physical and psychological symptoms. This case report emphasizes the importance of a thorough somatic differential diagnosis in the context of a suspected anorexia nervosa.
一名初步诊断为神经性厌食症的14岁艾迪生病女孩的病例报告:相似却又不同?原发性肾上腺皮质功能减退症(艾迪生病)是神经性厌食症罕见的鉴别诊断。本病例报告呈现了重要的鉴别诊断要点。我们根据CARE指南编写了一份14岁女性患者的病例报告,同时考虑了患者及其父母的观点。在症状出现约9个月后,通过特定的实验室诊断得出原发性肾上腺皮质功能减退症的诊断,症状包括体重突然减轻。重要的鉴别诊断要点包括体格检查中未出现身体意象障碍以及皮肤色素沉着显著。由于9个月来诊断不明,患者承受了巨大的心理社会负担。氢化可的松的诊断及替代治疗使身体和心理症状迅速改善。本病例报告强调了在疑似神经性厌食症的情况下进行全面躯体鉴别诊断的重要性。