School of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China.
School of Pharmacy, Nanjing Medical University, Nanjing, China.
Int J Technol Assess Health Care. 2024 Jan 15;40(1):e8. doi: 10.1017/S0266462323002799.
This study aims to gain insight into each attribute as presented in the value of implantable medical devices, quantify attributes' strength and their relative importance, and identify the determinants of stakeholders' preferences.
A mixed-methods design was used to identify attributes and levels reflecting stakeholders' preference toward the value of implantable medical devices. This design combined literature reviewing, expert's consultation, one-on-one interactions with stakeholders, and a pilot testing. Based on the design, six attributes and their levels were settled. Among 144 hypothetical profiles, 30 optimal choice sets were developed, and healthcare professionals (decision-makers, health technology assessment experts, hospital administrators, medical doctors) and patients as stakeholders in China were surveyed. A total of 134 respondents participated in the survey. Results were analyzed by mixed logit model and conditional logit model.
The results of the mixed logit model showed that all the six attributes had a significant impact on respondents' choices on implantable medical devices. Respondents were willing to pay the highest for medical devices that provided improvements in clinical safety, followed by increased clinical effectiveness, technology for treating severe diseases, improved implement capacity, and innovative technology (without substitutes).
The findings of DCE will improve the current evaluation on the value of implantable medical devices in China and provide decision-makers with the relative importance of the criteria in pricing and reimbursement decision-making of implantable medical devices.
本研究旨在深入了解医疗器械植入物价值呈现的各项属性，量化属性的强度及其相对重要性，并确定利益相关者偏好的决定因素。
采用混合方法设计来确定反映利益相关者对医疗器械植入物价值偏好的属性和水平。该设计结合了文献回顾、专家咨询、与利益相关者的一对一互动以及试点测试。基于该设计，确定了六个属性及其水平。在 144 个假设概况中，开发了 30 个最优选择集，并对中国的医疗保健专业人员（决策者、卫生技术评估专家、医院管理人员、医生）和患者等利益相关者进行了调查。共有 134 名受访者参与了调查。结果通过混合对数模型和条件对数模型进行分析。
混合对数模型的结果表明，所有六个属性对受访者对医疗器械植入物的选择都有重大影响。受访者愿意为在临床安全性方面提供改进、提高临床效果、治疗严重疾病的技术、提高实施能力以及创新技术（无替代品）的医疗器械支付最高费用。
DCE 的研究结果将改进中国目前对医疗器械植入物价值的评估，并为决策者提供医疗器械定价和报销决策中标准的相对重要性信息。
