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硅胶致颈部淋巴结病:隆胸术后一种罕见的并发症。

Silicone Cervical Lymphadenopathy: A Rare Complication After Breast Augmentation.

作者信息

Avgeri Caroline-Theodora, Sideris Giorgos, Margaris Ioannis, Tapponi Laith

机构信息

ENT Department, Royal Free London NHS Foundation Trust, London, GBR.

2nd ENT Department, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.

出版信息

Cureus. 2023 Dec 13;15(12):e50453. doi: 10.7759/cureus.50453. eCollection 2023 Dec.

DOI:10.7759/cureus.50453
PMID:38222151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10786187/
Abstract

A 66-year-old female patient, who had undergone breast augmentation 10 years ago, presented with unilateral neck pain, dysphagia, and hoarseness. Subsequent imaging revealed right-sided supraclavicular and axillary lymphadenopathy and a breast implant rupture on the same side. A lymph node core biopsy under sonographic guidance revealed silicone lymphadenopathy. Implant extirpation was offered to the patient. Cervical lymphadenopathy warrants an initial workup to exclude sinister chronic inflammatory or malignant conditions. Nonetheless, in cases of diagnostic uncertainty and a history of breast augmentation, the otolaryngologist should be cognizant of distal silicone lymphadenopathy. This condition is associated with silicone leakage and lymphatic dissemination of silicone particles. Even though silicone-related granuloma formation is a rare entity, its incidence is slowly rising as the population that has undergone breast augmentation grows older.

摘要

一名66岁女性患者,10年前接受过隆胸手术,现出现单侧颈部疼痛、吞咽困难和声音嘶哑。随后的影像学检查显示右侧锁骨上和腋窝淋巴结肿大,且同侧乳房植入物破裂。超声引导下的淋巴结核心活检显示为硅胶性淋巴结病。建议患者进行植入物摘除术。颈部淋巴结肿大需要进行初步检查以排除严重的慢性炎症或恶性疾病。然而,在诊断存在不确定性且有隆胸病史的情况下,耳鼻喉科医生应认识到远端硅胶性淋巴结病。这种情况与硅胶泄漏及硅胶颗粒的淋巴扩散有关。尽管硅胶相关肉芽肿的形成是一种罕见情况,但随着接受隆胸手术的人群年龄增长,其发病率正在缓慢上升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d74/10786187/763a380df320/cureus-0015-00000050453-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d74/10786187/839fd0e9c05f/cureus-0015-00000050453-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d74/10786187/763a380df320/cureus-0015-00000050453-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d74/10786187/839fd0e9c05f/cureus-0015-00000050453-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d74/10786187/763a380df320/cureus-0015-00000050453-i02.jpg

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本文引用的文献

1
Breast-implant Related Silicone Lymphadenopathy: Asteroid Bodies do not Always Equal Sarcoidosis!乳房植入物相关的硅酮淋巴结病:星状体并不总是等同于结节病!
Int J Surg Pathol. 2023 Sep;31(6):1099-1104. doi: 10.1177/10668969221129890. Epub 2022 Oct 30.
2
Late migration of silicon as a complication to breast transplant rupture: Case report and literature review.硅的晚期迁移作为乳房移植破裂的一种并发症:病例报告及文献综述
Int J Surg Case Rep. 2021 Aug;85:106241. doi: 10.1016/j.ijscr.2021.106241. Epub 2021 Jul 27.
3
Silicone granuloma: a cause of cervical lymphadenopathy following breast implantation.
硅酮肉芽肿:乳房植入术后引起的颈淋巴结病的一个原因。
BMJ Case Rep. 2021 Mar 3;14(3):e239395. doi: 10.1136/bcr-2020-239395.
4
Breast implant-associated anaplastic large cell lymphoma: a review.乳房植入物相关间变大细胞淋巴瘤:综述。
Mod Pathol. 2019 Feb;32(2):166-188. doi: 10.1038/s41379-018-0134-3. Epub 2018 Sep 11.
5
Clinicopathologic Features and Prognostic Impact of Lymph Node Involvement in Patients With Breast Implant-associated Anaplastic Large Cell Lymphoma.乳腺假体相关性间变大细胞淋巴瘤患者淋巴结累及的临床病理特征及预后影响。
Am J Surg Pathol. 2018 Mar;42(3):293-305. doi: 10.1097/PAS.0000000000000985.
6
Sonographic differentiation between lymphatic and metastatic diseases in cervical lymphadenopathy.颈部淋巴结病中淋巴疾病与转移性疾病的超声鉴别诊断
Laryngoscope. 2018 Apr;128(4):859-863. doi: 10.1002/lary.26837. Epub 2017 Aug 22.
7
Silicone granuloma from ruptured breast implants as a cause of cervical lymphadenopathy.乳房植入物破裂导致的硅酮肉芽肿作为颈部淋巴结病的一个病因
Ann R Coll Surg Engl. 2016 Sep;98(7):e118-20. doi: 10.1308/rcsann.2016.0166. Epub 2016 May 11.
8
Cervical silicone lymphadenopathy.颈部硅胶性淋巴结病
Br J Oral Maxillofac Surg. 2016 Jul;54(6):e52-4. doi: 10.1016/j.bjoms.2016.01.011. Epub 2016 Jan 28.
9
Thoracic outlet syndrome following breast implant rupture.乳房植入物破裂后的胸廓出口综合征
Plast Reconstr Surg Glob Open. 2015 Apr 7;3(3):e331. doi: 10.1097/GOX.0000000000000295. eCollection 2015 Mar.
10
Subconjunctival and orbital silicone oil granuloma (siliconoma) complicating intravitreal silicone oil tamponade.玻璃体内硅油填塞术后并发的结膜下及眼眶硅油肉芽肿(硅瘤)。
Case Rep Ophthalmol Med. 2014;2014:686973. doi: 10.1155/2014/686973. Epub 2014 Apr 24.