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理解癌症护理和预测负担:一种分析和机器学习方法。

Understanding Cancer Caregiving and Predicting Burden: An Analytics and Machine Learning Approach.

机构信息

Innovation Empowerment and Design Application (IDEA) Lab Center for Information Systems & Technology Claremont Graduate University, Claremont, California, USA.

出版信息

AMIA Annu Symp Proc. 2024 Jan 11;2023:243-252. eCollection 2023.

PMID:38222371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10785947/
Abstract

Cancer caregivers are often informal family members who may not be prepared to adequately meet the needs of patients and often experience high stress along with significant physical, emotional, and financial burdens. Accurate prediction of caregiver's burden level is highly valuable for early intervention and support. In this study, we used several machine learning approaches to build prediction models from the National Alliance for Caregiving/AARP dataset. We performed data cleansing and imputation on the raw data to give us a working dataset of cancer caregivers. Then a series of feature selection methods were used to identify predictive risk factors for burden level. Using supervised machine learning classifiers, we achieved reasonably good prediction performance (Accuracy ∼ 0.94; AUC ∼ 0.97; F1∼ 0.93). We identify a small set of 15 features that are strong predictors of burden and can be used to build Clinical Decision Support Systems.

摘要

癌症护理人员通常是非正式的家庭成员,他们可能没有准备好充分满足患者的需求,并且经常承受高压力以及巨大的身体、情感和经济负担。准确预测护理人员的负担水平对于早期干预和支持非常有价值。在这项研究中,我们使用了几种机器学习方法,从全国照顾者联盟/美国退休人员协会(National Alliance for Caregiving/AARP)数据集构建预测模型。我们对原始数据进行了数据清理和插补,为我们提供了一个可用于癌症护理人员的工作数据集。然后,使用了一系列特征选择方法来确定负担水平的预测风险因素。使用监督机器学习分类器,我们实现了相当不错的预测性能(Accuracy∼0.94;AUC∼0.97;F1∼0.93)。我们确定了一小部分 15 个特征,这些特征是负担的强预测因子,可以用于构建临床决策支持系统。

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本文引用的文献

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Prediction of caregiver burden in amyotrophic lateral sclerosis: a machine learning approach using random forests applied to a cohort study.预测肌萎缩侧索硬化症患者的照护者负担:使用随机森林的机器学习方法对队列研究进行分析。
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2
A systematic review of cancer caregiver interventions: Appraising the potential for implementation of evidence into practice.癌症照顾者干预措施的系统评价:评估将证据应用于实践的潜力。
Psychooncology. 2019 Apr;28(4):687-701. doi: 10.1002/pon.5018. Epub 2019 Mar 7.
3
The financial burden and distress of patients with cancer: Understanding and stepping-up action on the financial toxicity of cancer treatment.癌症患者的经济负担和困境:了解并加强对癌症治疗的财务毒性的行动。
CA Cancer J Clin. 2018 Mar;68(2):153-165. doi: 10.3322/caac.21443. Epub 2018 Jan 16.
4
Integrated Machine Learning Approaches for Predicting Ischemic Stroke and Thromboembolism in Atrial Fibrillation.用于预测心房颤动患者缺血性卒中和血栓栓塞的集成机器学习方法
AMIA Annu Symp Proc. 2017 Feb 10;2016:799-807. eCollection 2016.
5
Caring for caregivers and patients: Research and clinical priorities for informal cancer caregiving.关爱照护者与患者:癌症非正规照护的研究与临床重点
Cancer. 2016 Jul 1;122(13):1987-95. doi: 10.1002/cncr.29939. Epub 2016 Mar 17.
6
Physical, psychosocial, relationship, and economic burden of caring for people with cancer: a review.照顾癌症患者的身体、心理社会、关系和经济负担:综述。
J Oncol Pract. 2013 Jul;9(4):197-202. doi: 10.1200/JOP.2012.000690. Epub 2012 Dec 4.
7
Type 2 diabetes risk forecasting from EMR data using machine learning.利用机器学习从电子病历数据预测2型糖尿病风险
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Physical well-being of oncology caregivers: an important quality-of-life domain.肿瘤患者照护者的身体健康:一个重要的生活质量领域。
Semin Oncol Nurs. 2012 Nov;28(4):226-35. doi: 10.1016/j.soncn.2012.09.005.
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Role recognition and changes to self-identity in family caregivers of people with advanced cancer: a qualitative study.晚期癌症患者家庭照顾者的角色认知和自我认同变化:一项定性研究。
Support Care Cancer. 2012 Jun;20(6):1175-81. doi: 10.1007/s00520-011-1194-9. Epub 2011 May 25.
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Objective burden, resources, and other stressors among informal cancer caregivers: a hidden quality issue?非专业癌症护理者的客观负担、资源和其他压力源:一个隐藏的质量问题?
Psychooncology. 2011 Jan;20(1):44-52. doi: 10.1002/pon.1703.