Youngkin E Q, Miller L G
Nurse Pract. 1987 Feb;12(2):17-8, 23, 26-8.
Three triphasic oral contraceptive preparations are currently being widely used in the United States. These are Ortho-Novum 7/7/7 (Ortho Pharmaceutical), Tri-Norinyl (Syntex) and Triphasil (Wyeth). The hormone manipulation in these formulations more closely mimics the normal menstrual cycle and decreases the total amount of hormone delivered. These drugs were formulated to decrease menstrual irregularities and nuisance side effects and increase menstrual control, while maintaining efficacy and safety. This article describes these products, their mechanisms of action, efficacy and selected areas of concern for clinical practice in relation to side effects, safety and menstrual control. Findings and suggestions related to the therapeutic administration, patient use, counseling and management of these newer oral contraceptives will assist the nurse practitioner in providing optimum care to the consumer.
目前，三种三相口服避孕药制剂在美国被广泛使用。它们分别是炔诺酮炔雌醇片（7/7/7）（惠氏制药公司）、复方炔诺酮片（先灵葆雅公司）和三相片（惠氏公司）。这些制剂中的激素调控更接近正常月经周期，并减少了激素的总给药量。这些药物的配方旨在减少月经不规律和令人烦恼的副作用，并加强月经调控，同时保持有效性和安全性。本文介绍了这些产品、它们的作用机制、有效性以及在副作用、安全性和月经调控方面临床实践中需要关注的特定领域。与这些新型口服避孕药的治疗给药、患者使用、咨询和管理相关的研究结果和建议，将有助于执业护士为消费者提供最佳护理。
