Pandit Kamal, Rawal Aastha, Maskey Himang Man Singh, Nepal Gaurav
Department of Ophthalmology, Maharjgunj Medical Campus, Tribhuvan University, Institute of Medicine, Maharajgunj, Kathmandu.
Department of Pharmacy, Manmohan Memorial Medical College and Teaching Hospital, Kathmandu, Nepal.
Ann Med Surg (Lond). 2023 Nov 22;86(1):392-400. doi: 10.1097/MS9.0000000000001523. eCollection 2024 Jan.
Snakebites, a major health concern in developing countries, affect rural farming communities. Venom, primarily neurotoxin, injected during a snake bite disrupts the nervous system, causing symptoms like muscle weakness, paralysis, altered sensation, and coordination issues. This review focuses on evaluating neurological and neuro-ophthalmological manifestations associated with snakebites.
A database search was conducted in EMBASE and PubMed for studies published from 2000 to 2023. The investigation centered on examining neurological and neuro-ophthalmological symptoms and signs, treatment approaches, treatment outcomes, and long-term complications of snake bites.
Neurological and neuro-ophthalmological symptoms were common in both neurotoxic and hemotoxic snake bites, especially in neurotoxic cases. Ptosis was a prevalent manifestation across various snake bites, along with respiratory paralysis, limb weakness, dysphasia, and visual disturbances in some instances. However, most patients improved without residual neurological symptoms after treatment.
Understanding patterns of neurological manifestations contributes valuable insights for the comprehensive management of snakebite.
蛇咬伤是发展中国家主要的健康问题，影响农村务农社区。蛇咬伤时注入的毒液主要是神经毒素，会扰乱神经系统，导致肌肉无力、麻痹、感觉改变和协调问题等症状。本综述重点评估与蛇咬伤相关的神经和神经眼科表现。
在EMBASE和PubMed数据库中检索2000年至2023年发表的研究。调查集中于检查蛇咬伤的神经和神经眼科症状及体征、治疗方法、治疗结果和长期并发症。
神经和神经眼科症状在神经毒性和血液毒性蛇咬伤中都很常见，尤其是在神经毒性病例中。上睑下垂是各种蛇咬伤中的常见表现，在某些情况下还伴有呼吸麻痹、肢体无力、吞咽困难和视觉障碍。然而，大多数患者治疗后症状改善，无残留神经症状。
了解神经表现模式有助于为蛇咬伤的综合管理提供有价值的见解。
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