McNeeley S G, Baselski V S, Ryan G M
Obstet Gynecol. 1987 Apr;69(4):550-3.
Two commercially available rapid bacteriuria screening procedures were evaluated for routine screening for 10(4) or more colony forming units per milliliter of pathogenic bacteria in two female patient populations. In 694 obstetric patients with 56 cases of significant bacteriuria, the sensitivity, specificity, positive predictive, and negative predictive values, respectively, were as follows: for Chemstrip LN, 69.6, 83.4, 26.9, and 96.9%; and for Bac-T-Screen, 96.4, 56.0, 16.1, and 99.4%. In 143 nonpregnant females with 32 cases of significant bacteriuria, these values were: for Chemstrip LN, 71.9, 75.7, 46.0, and 90.3%; and for Bac-T-Screen, 84.4, 65.8, 41.5, and 93.6%. These results indicate that the LN strip did not have acceptable sensitivity in either patient group. The Bac-T-Screen had better sensitivity, particularly for obstetric patients; however, a high false-positive rate and high cost per test may restrict its use in those clinical settings where culture is available and cost-effective.
对两种市售的快速菌尿筛查方法进行了评估，以用于对两类女性患者群体进行常规筛查，检测每毫升尿液中是否存在10⁴或更多菌落形成单位的病原菌。在694例产科患者中，有56例存在显著菌尿，Chemstrip LN的灵敏度、特异度、阳性预测值和阴性预测值分别如下：69.6%、83.4%、26.9%和96.9%；Bac-T-Screen的相应值分别为：96.4%、56.0%、16.1%和99.4%。在143例非妊娠女性中，有32例存在显著菌尿，Chemstrip LN的上述值分别为：71.9%、75.7%、46.0%和90.3%；Bac-T-Screen的相应值分别为：84.4%、65.8%、41.5%和93.6%。这些结果表明，LN试纸条在两类患者群体中的灵敏度均不可接受。Bac-T-Screen具有更好的灵敏度，尤其是对产科患者；然而，其高假阳性率和每次检测的高成本可能会限制其在可进行培养且成本效益高的临床环境中的应用。
