Ozeki S, Kawamura T, Nishino Y, Ishihara S, Ban Y, Kawada Y
Department of Urology, Gifu University School of Medicine.
Hinyokika Kiyo. 1997 Dec;43(12):861-5.
A nitrite test for bacteriuria was compared with routine microscopic examination in 1,318 clinical urine specimens and with bacterial culture in 132. Sensitivity, specificity, positive predictive value and accuracy rate are as follows; for diagnosis of bacteriuria more than 10(4) CFU/ml, 53.4%, 88.6%, 90.4 and 65.2%, respectively; for more than 10(5) CFU/ml, 55.4%, 87.8%, 88.4% and 67.2%, respectively. The positive rate for the nitrite test was 21.4% for bacteriuria of > or = 10(4) CFU/ml in gram positive cocci and 56.9% in gram negative rods. False negative results were obtained from gram positive cocci without nitrate reductive activity or from patients with acute uncomplicated cystitis because of insufficient incubation time in urinary tract. However, this simple test is valuable in the detection of bacteriuria in clinical practice with high specificity.
对1318份临床尿液标本进行了亚硝酸盐检测菌尿试验，并与常规显微镜检查进行比较，对132份标本进行了细菌培养。其敏感性、特异性、阳性预测值和准确率如下：对于诊断菌尿≥10⁴CFU/ml，分别为53.4%、88.6%、90.4%和65.2%；对于≥10⁵CFU/ml，分别为55.4%、87.8%、88.4%和67.2%。对于革兰氏阳性球菌菌尿≥10⁴CFU/ml，亚硝酸盐检测阳性率为21.4%，对于革兰氏阴性杆菌为56.9%。革兰氏阳性球菌无硝酸盐还原活性或急性单纯性膀胱炎患者因尿路孵育时间不足会出现假阴性结果。然而，这项简单的检测在临床实践中对菌尿的检测具有很高的特异性，很有价值。
