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肾移植受者中一例由淀粉样变性导致页状肾的罕见病例:病例报告

An Intriguing Case of Amyloidosis Leading to PAGE Kidney in a Post Renal Transplant Recipient: A Case Report.

作者信息

Bagai Sahil, Sanjeevani Scienthia, Khullar Dinesh, Duggal Rajan, Prasad Pallavi, Saxena Vivek

机构信息

Department of Nephrology and renal transplant medicine, Max Super Speciality Hospital, Saket, Delhi India.

Department of Pathology, BLK-Max Hospital, Delhi, India.

出版信息

Indian J Clin Biochem. 2024 Jan;39(1):146-150. doi: 10.1007/s12291-022-01072-6. Epub 2022 Sep 9.

Abstract

UNLABELLED

Amyloidosis is an infiltrative disease where amyloid fibrils get deposited in the organs like kidney, liver and spleen. Amyloid deposition in the kidneys classically meant deposition in the glomeruli and mesangium until 2008 when interstitial amyloid deposits were isolated and named as` Leukocyte cell-derived chemotaxin 2-associated amyloidosis. It is a progressive disease which clinically manifests as slowly progressive renal dysfunction and/or proteinuria. Our case 34 year old renal transplant recipient underwent graft biopsy post transplantation which revealed interstitial LECT-2 amyloid deposits. Unfortunately, he developed page kidney post biopsy which was managed conservatively with percutaneous drainage.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s12291-022-01072-6.

摘要

未标注

淀粉样变性是一种浸润性疾病,其中淀粉样纤维沉积在肾脏、肝脏和脾脏等器官中。直到2008年分离出肾间质淀粉样沉积物并将其命名为“白细胞衍生趋化因子2相关淀粉样变性”之前,肾脏中的淀粉样沉积传统上是指在肾小球和系膜中的沉积。它是一种进行性疾病,临床上表现为缓慢进展的肾功能不全和/或蛋白尿。我们的病例是一名34岁的肾移植受者,移植后进行了移植肾活检,结果显示肾间质LECT-2淀粉样沉积。不幸的是,他活检后出现了肾周积液,通过经皮引流进行了保守治疗。

补充信息

在线版本包含可在10.1007/s12291-022-01072-6获取的补充材料。

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本文引用的文献

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