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颈椎前路手术是否会增加发生阻塞性睡眠呼吸暂停的可能性?一项珍珠潜水研究。

Does Anterior Cervical Spine Surgery Increase the Likelihood of Developing Obstructive Sleep Apnea? A Pearldiver Study.

机构信息

Pennsylvania Hospital, Philadelphia, Pennsylvania, USA.

Pennsylvania Hospital, Philadelphia, Pennsylvania, USA.

出版信息

World Neurosurg. 2024 Apr;184:e72-e75. doi: 10.1016/j.wneu.2024.01.045. Epub 2024 Jan 13.

DOI:10.1016/j.wneu.2024.01.045
PMID:38224907
Abstract

OBJECTIVES

Literature is sparse on the development of obstructive sleep apnea (OSA) after anterior cervical spine surgery and includes few case reports. Our objective is to evaluate the role of anterior cervical spine surgery as a risk factor for developing OSA.

METHODS

A retrospective cohort study was performed utilizing the M157 subset of the PearlDiver national database. Two matched cohorts of patients were identified based on anterior cervical spine surgery using CPT codes. ICD-9 and 10 was used to identify patients who developed OSA within one year time frame in both the cohorts. Relative risk of OSA was calculated for the study and risk factors for developing OSA in the cohort of anterior cervical surgery were evaluated using logistic regression.

RESULTS

The 2 cohorts contained 277,475 patients each. The 1-year incidence rate of OSA in those who undergo anterior cervical spine surgery is 3.5% and is 3.1% in the control group. The relative risk of OSA in the surgery group is 1.13 times compared to the control. Multilevel cervical spine surgery and surgery performed for spondylosis had a higher risk of developing OSA.

CONCLUSIONS

Anterior cervical spine surgery is associated with an increased risk of developing OSA within one year of surgery. Timely diagnosis and management of OSA in patients who underwent anterior cervical spine surgery can help prevent morbidity and improve quality of life (QOL).

摘要

目的

文献中关于颈椎前路手术后阻塞性睡眠呼吸暂停(OSA)的发展的资料很少,且仅包含少数病例报告。我们的目的是评估颈椎前路手术作为发生 OSA 的危险因素的作用。

方法

利用 PearlDiver 国家数据库的 M157 子集进行回顾性队列研究。根据 CPT 代码识别出两组接受颈椎前路手术的患者。使用 ICD-9 和 10 在两个队列中确定了一年内发生 OSA 的患者。计算了研究的 OSA 相对风险,并使用逻辑回归评估了颈椎前路手术队列中发生 OSA 的风险因素。

结果

两个队列各包含 277475 名患者。接受颈椎前路手术的患者中,1 年内 OSA 的发生率为 3.5%,对照组为 3.1%。手术组发生 OSA 的相对风险是对照组的 1.13 倍。多节段颈椎手术和因颈椎病进行的手术发生 OSA 的风险更高。

结论

颈椎前路手术后 1 年内发生 OSA 的风险增加。对接受颈椎前路手术的患者及时诊断和治疗 OSA 有助于预防发病率并提高生活质量(QOL)。

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引用本文的文献

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Obstructive Sleep Apnea is Associated With Increased Rates of Acute Respiratory Failure, Length of Stay, and Hospital Costs in Patients Undergoing Elective Single-Level Anterior Cervical Discectomy and Fusion.阻塞性睡眠呼吸暂停与择期单节段颈椎前路椎间盘切除融合术患者急性呼吸衰竭发生率增加、住院时间延长及住院费用增加相关。
Global Spine J. 2025 Mar 28:21925682251333324. doi: 10.1177/21925682251333324.