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门诊前路颈椎间盘切除术和融合术与更高的翻修手术和围手术期并发症风险相关:一项基于大型全国性数据库的分析。

Ambulatory anterior cervical discectomy and fusion is associated with a higher risk of revision surgery and perioperative complications: an analysis of a large nationwide database.

机构信息

Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, 1250 16th St., Santa Monica, CA 90404.

Department of Orthopaedic Surgery, Keck School of Medicine of USC, 1450 San Pablo St., Suite 5400, Los Angeles, CA, 90033.

出版信息

Spine J. 2018 Jul;18(7):1180-1187. doi: 10.1016/j.spinee.2017.11.012. Epub 2017 Nov 16.

DOI:10.1016/j.spinee.2017.11.012
PMID:29155340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6291305/
Abstract

BACKGROUND CONTEXT

With the changing landscape of health care, outpatient spine surgery is being more commonly performed to reduce cost and to improve efficiency. Anterior cervical discectomy and fusion (ACDF) is one of the most common spine surgeries performed and demand is expected to increase with an aging population.

PURPOSE

The objective of this study was to determine the nationwide trends and relative complication rates associated with outpatient ACDF.

STUDY DESIGN/SETTING: This is a large-scale retrospective case control study.

PATIENT SAMPLE

The patient sample included Humana-insured patients who underwent one- to two-level ACDF as either outpatients or inpatients from 2011 to 2016 OUTCOME MEASURES: The outcome measures included incidence and the adjusted odds ratio (OR) of postoperative medical and surgical complications within 1 year of the index surgery.

MATERIALS AND METHODS

A retrospective review was performed of the PearlDiver Humana insurance records database to identify patients undergoing one- to two-level ACDF (Current Procedural Terminology [CPT]-22551 and International Classification of Diseases [ICD]-9-816.2) as either outpatients or inpatients from 2011 to 2016. The incidence of perioperative medical and surgical complications was determined by querying for relevant ICD and CPT codes. Multivariate logistic regression adjusting for age, gender, and Charlson Comorbidity Index was used to calculate ORs of complications among outpatients relative to inpatients undergoing ACDF.

RESULTS

Cohorts of 1,215 patients who underwent outpatient ACDF and 10,964 patients who underwent inpatient ACDF were identified. The median age was in the 65-69 age group for both cohorts. The annual relative incidence of outpatient ACDF increased from 0.11 in 2011 to 0.22 in 2016 (R=0.82, p=.04). Adjusting for age, gender, and comorbidities, patients undergoing outpatient ACDF were more likely to undergo revision surgery for posterior fusion at both 6 months (OR 1.58, confidence interval [CI] 1.27-1.96, p<.001) and 1 year (OR 1.79, CI 1.51-2.13, p<.001) postoperatively. Outpatient ACDF was also associated with a higher likelihood of revision anterior fusion at 1 year postoperatively (OR 1.46, CI 1.26-1.70, p<.001). Among medical complications, postoperative acute renal failure was more frequently associated with outpatient ACDF than inpatient ACDF (OR 1.25, CI 1.06-1.49, p=.010). Adjusted rates of all other queried surgical and medical complications were comparable.

CONCLUSIONS

Outpatient ACDF is increasing in frequency nationwide over the past several years. Nationwide data demonstrate a greater risk of perioperative surgical complications, including revision anterior and posterior fusion, as well as a higher risk of postoperative acute renal failure. Candidates for outpatient ACDF should be counseled and carefully selected to reduce these risks.

摘要

背景

随着医疗保健格局的变化,越来越多地进行门诊脊柱手术以降低成本和提高效率。颈椎前路椎间盘切除术和融合术(ACDF)是最常见的脊柱手术之一,预计随着人口老龄化,需求将会增加。

目的

本研究旨在确定与门诊 ACDF 相关的全国趋势和相对并发症发生率。

研究设计/设置:这是一项大规模的回顾性病例对照研究。

患者样本

患者样本包括 2011 年至 2016 年期间接受 1 至 2 级 ACDF 的 Humana 保险患者,无论是门诊还是住院患者。

研究结果

确定了 1215 例门诊 ACDF 患者和 10964 例住院 ACDF 患者的队列。两个队列的中位年龄均为 65-69 岁。门诊 ACDF 的年度相对发生率从 2011 年的 0.11 增加到 2016 年的 0.22(R=0.82,p=.04)。调整年龄、性别和合并症后,门诊 ACDF 患者在术后 6 个月(OR 1.58,95%置信区间 [CI] 1.27-1.96,p<.001)和 1 年(OR 1.79,CI 1.51-2.13,p<.001)时更有可能进行后路融合翻修手术。门诊 ACDF 术后 1 年也更有可能进行前路融合翻修(OR 1.46,CI 1.26-1.70,p<.001)。在医疗并发症方面,术后急性肾衰竭与门诊 ACDF 的相关性高于住院 ACDF(OR 1.25,CI 1.06-1.49,p=.010)。调整后的所有其他查询手术和医疗并发症的发生率相当。

结论

过去几年,全国范围内门诊 ACDF 的频率呈上升趋势。全国数据显示,围手术期手术并发症的风险增加,包括前路和后路融合翻修,以及术后急性肾衰竭的风险增加。门诊 ACDF 的候选者应接受咨询并精心挑选,以降低这些风险。

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