Department of Biology, University of Rochester, Rochester, NY, USA.
Division of General Academic Pediatrics, Massachusetts General for Children, Boston, MA, USA.
Nicotine Tob Res. 2024 Jul 22;26(8):984-990. doi: 10.1093/ntr/ntae003.
Increasing electronic cigarette use among youth has led to a need for a novel intensity measure of e-cigarette use and its association with nicotine addiction variables.
Using a cross-sectional study of the 2018-2019 PATH Wave 5 Youth survey, a new intensity metric of e-cigarette use, the average number of puffs per month as a function of frequency (days of use per month), number of uses per day and number of puffs per use, was developed for adolescent e-cigarette users. Using logistic regression, standard addiction measures were tested for association with higher quartile (Q) of e-cigarette intensity: Q1 (1-5 puffs), Q2 (6-50 puffs), Q3 (51-528 puffs), and Q4 (529 + puffs).
Among 1051 current youth e-cigarette users, cravings were associated with greater intensity of use (Q2: aOR = 1.90, 95% CI: 0.94-3.87; Q3: aOR = 6.91, 95% CI: 3.25-14.69; and Q4: aOR = 21.48, 95% CI: 10.03-45.97). Craving associations exceeded the corresponding aORs for the identical regression using the frequency of use. Higher intensity was significantly associated with being an older adolescent (aOR = 1.85), best friend use (aOR: 3.35), not thinking about quitting (aOR: 2.51), and lower perceived addiction (aOR: 1.95).
This study found that an intensity metric (puffs per month) was strongly associated with cravings, best friend use, harm perception, and lack of intention to quit. This metric provides a more accurate picture of the intensity of youth e-cigarette use than other commonly used measures and may be important for understanding the current and future impact of the youth e-cigarette epidemic.
Adolescent addiction to e-cigarettes affects learning, memory, and attention. However, it is unknown whether the intensity of use, puffs per month, differs from frequency, days of use per month, and in relation to addiction measures. This study provides evidence that high-intensity use characterized by puffs per month has a stronger association with cravings compared to frequency, which suggests puffs per month may be a better measure of nicotine exposure. This new intensity metric may give insights into youth e-cigarette use patterns, addiction, and appropriate treatment of intense but intermittent users.
青少年使用电子烟的人数不断增加,这使得我们需要一种新的电子烟使用强度衡量指标,并研究其与尼古丁成瘾变量的关系。
本研究使用 2018-2019 年 PATH 波 5 青年调查的横断面研究,为青少年电子烟使用者开发了一种电子烟使用新的强度衡量指标,即平均每月吸电子烟口数与使用频率(每月使用天数)、每日使用次数和每次使用吸电子烟口数的函数。使用逻辑回归,对标准成瘾衡量指标进行了测试,以评估其与电子烟使用强度更高四分位数(Q)的关联:Q1(1-5 口)、Q2(6-50 口)、Q3(51-528 口)和 Q4(529+口)。
在 1051 名当前使用电子烟的青少年中,烟瘾与更高的电子烟使用强度有关(Q2:aOR=1.90,95%CI:0.94-3.87;Q3:aOR=6.91,95%CI:3.25-14.69;Q4:aOR=21.48,95%CI:10.03-45.97)。烟瘾的关联超过了使用相同回归方法时使用频率的相应 aOR。更高的强度与年龄较大的青少年(aOR=1.85)、最好的朋友使用(aOR:3.35)、不考虑戒烟(aOR:2.51)和较低的感知成瘾(aOR:1.95)显著相关。
本研究发现,一种强度衡量指标(每月吸电子烟口数)与烟瘾、最好的朋友使用、危害感知和缺乏戒烟意愿密切相关。与其他常用衡量指标相比,该指标更能准确地描述青少年电子烟使用的强度,对于理解当前和未来青少年电子烟流行的影响可能具有重要意义。
青少年对电子烟的成瘾会影响学习、记忆和注意力。然而,目前尚不清楚使用强度、每月吸电子烟口数是否与使用频率(每月使用天数)不同,以及与成瘾衡量指标的关系。本研究提供的证据表明,以每月吸电子烟口数为特征的高强度使用与烟瘾的关联比使用频率更强,这表明每月吸电子烟口数可能是衡量尼古丁暴露的更好指标。这种新的强度衡量指标可能为青少年电子烟使用模式、成瘾以及对间歇性高强度使用者的适当治疗提供新的见解。