• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

根据最新的 ESC 指南,常规实践中房颤的当前管理:EHRA 医师调查-我们如何处理有争议的方法?

Current management of atrial fibrillation in routine practice according to the last ESC guidelines: an EHRA physician survey-how are we dealing with controversial approaches?

机构信息

Department of Cardiology, Hospital de la Santa Creu i Sant Pau, IR SANT PAU, Universitat Autònoma de Barcelona, CIBERCV, Sant Antoni M. Claret 167, 08025 Barcelona, Spain.

Arrhythmia Unit, Careggi University Hospital, Florence, Italy.

出版信息

Europace. 2024 Feb 1;26(2). doi: 10.1093/europace/euae012.

DOI:10.1093/europace/euae012
PMID:38227804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10869216/
Abstract

AIMS

Although guidelines for the management of atrial fibrillation (AF) are regularly published, many controversial issues remain, limiting their implementation. We aim to describe current clinical practice among European Heart Rhythm Association (EHRA) community according to last guidelines.

METHODS AND RESULTS

A 30 multiple-choice questionnaire covering the most controversial topics related to AF management was distributed through the EHRA Research Network, National Societies, and social media between January and February 2023. One hundred and eighty-one physicians responded the survey, 61% from university hospitals. Atrial fibrillation screening in high-risk patients is regularly performed by 57%. Only 42% has access to at least one programme aiming at diagnosing/managing comorbidities and lifestyle modifications, with marked heterogeneity between countries. Direct oral anticoagulants are the preferred antithrombotic (97%). Rhythm control is the preferred strategy in most AF phenotypes: symptomatic vs. asymptomatic paroxysmal AF (97% vs. 77%), low vs. high risk for recurrence persistent AF (90% vs. 72%), and permanent AF (20%). I-C drugs and amiodarone are preferred while dronedarone and sotalol barely used. Ablation is the first-line therapy for symptomatic paroxysmal AF (69%) and persistent AF with markers of atrial disease (57%) and is performed independently of symptoms by 15%. In persistent AF, 68% performs only pulmonary vein isolation and 32% also additional lesions.

CONCLUSION

There is marked heterogeneity in AF management and limited accordance to last guidelines in the EHRA community. Most of the discrepancies are related to the main controversial issues, such as those related to AF screening, management of comorbidities, pharmacological treatment, and ablation strategy.

摘要

目的

尽管已经定期发布了心房颤动(AF)管理指南,但仍存在许多有争议的问题,限制了其实施。我们旨在根据最新指南描述欧洲心律协会(EHRA)社区当前的临床实践。

方法和结果

在 2023 年 1 月至 2 月期间,通过 EHRA 研究网络、国家协会和社交媒体,向 181 名医生分发了一份涵盖与 AF 管理最相关的 30 个多项选择题的调查问卷。61%的应答者来自大学医院。57%的医生定期对高危患者进行房颤筛查。只有 42%的医生可以获得至少一个旨在诊断/管理合并症和生活方式改变的项目,各国之间存在明显的差异。直接口服抗凝剂是首选的抗血栓药物(97%)。在大多数 AF 表型中,节律控制是首选策略:症状性与无症状阵发性 AF(97%与 77%)、低复发风险与高复发风险持续性 AF(90%与 72%)、永久性 AF(20%)。I-C 类药物和胺碘酮是首选药物,而多非利特和索他洛尔很少使用。消融是症状性阵发性 AF(69%)和有房性疾病标志物的持续性 AF(57%)的一线治疗方法,15%的医生在没有症状的情况下进行消融。在持续性 AF 中,68%的医生仅进行肺静脉隔离,32%的医生还进行额外的消融。

结论

EHRA 社区在 AF 管理方面存在明显的异质性,且与最新指南的一致性有限。大多数差异与主要的争议问题有关,例如与 AF 筛查、合并症管理、药物治疗和消融策略有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/0f320bb58308/euae012f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/ed4bdae2bf6a/euae012_ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/adaab195cd62/euae012f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/116bf78e26e1/euae012f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/1044c4d9a2cf/euae012f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/83d95c33bf81/euae012f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/0f320bb58308/euae012f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/ed4bdae2bf6a/euae012_ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/adaab195cd62/euae012f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/116bf78e26e1/euae012f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/1044c4d9a2cf/euae012f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/83d95c33bf81/euae012f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/10869216/0f320bb58308/euae012f5.jpg

相似文献

1
Current management of atrial fibrillation in routine practice according to the last ESC guidelines: an EHRA physician survey-how are we dealing with controversial approaches?根据最新的 ESC 指南,常规实践中房颤的当前管理:EHRA 医师调查-我们如何处理有争议的方法?
Europace. 2024 Feb 1;26(2). doi: 10.1093/europace/euae012.
2
Management of atrial fibrillation in seven European countries after the publication of the 2010 ESC Guidelines on atrial fibrillation: primary results of the PREvention oF thromboemolic events--European Registry in Atrial Fibrillation (PREFER in AF).2010 年 ESC 心房颤动指南发布后七个欧洲国家的心房颤动管理:预防血栓栓塞事件-心房颤动欧洲登记研究(PREFER in AF)的初步结果。
Europace. 2014 Jan;16(1):6-14. doi: 10.1093/europace/eut263. Epub 2013 Oct 1.
3
Patient selection, peri-procedural management, and ablation techniques for catheter ablation of atrial fibrillation: an EHRA survey.经导管消融治疗心房颤动的患者选择、围术期管理和消融技术:EHRA 调查。
Europace. 2023 Feb 16;25(2):667-675. doi: 10.1093/europace/euac236.
4
Work-up and management of lone atrial fibrillation: results of the European Heart Rhythm Association Survey.孤立性心房颤动的检查和处理:欧洲心律协会调查的结果。
Europace. 2014 Oct;16(10):1521-3. doi: 10.1093/europace/euu277.
5
The challenge of managing multimorbid atrial fibrillation: a pan-European European Heart Rhythm Association (EHRA) member survey of current management practices and clinical priorities.管理多重合并症心房颤动的挑战:一项泛欧欧洲心脏节律协会(EHRA)成员调查,涉及当前的管理实践和临床重点。
Europace. 2022 Dec 9;24(12):2004-2014. doi: 10.1093/europace/euac136.
6
Antithrombotic therapy in atrial fibrillation associated with valvular heart disease: a joint consensus document from the European Heart Rhythm Association (EHRA) and European Society of Cardiology Working Group on Thrombosis, endorsed by the ESC Working Group on Valvular Heart Disease, Cardiac Arrhythmia Society of Southern Africa (CASSA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), South African Heart (SA Heart) Association and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE).心房颤动合并心脏瓣膜病的抗栓治疗:欧洲心律协会(EHRA)和欧洲心脏病学会血栓工作组的联合共识文件,得到 ESC 心脏瓣膜病工作组、南非心脏协会(SA Heart)、心律学会(HRS)、亚太心律学会(APHRS)、南非心脏协会(SA Heart)和拉丁美洲心脏刺激和电生理学会(SOLEACE)的认可。
Europace. 2017 Nov 1;19(11):1757-1758. doi: 10.1093/europace/eux240.
7
A prospective survey in European Society of Cardiology member countries of atrial fibrillation management: baseline results of EURObservational Research Programme Atrial Fibrillation (EORP-AF) Pilot General Registry.一项在欧洲心脏病学会成员国中进行的关于心房颤动管理的前瞻性调查:EURObservational Research Programme Atrial Fibrillation(EORP-AF)试点综合登记处的基线结果。
Europace. 2014 Mar;16(3):308-19. doi: 10.1093/europace/eut373. Epub 2013 Dec 17.
8
Rhythm monitoring, success definition, recurrence, and anticoagulation after atrial fibrillation ablation: results from an EHRA survey.房颤消融术后的节律监测、成功定义、复发和抗凝:EHRA 调查结果。
Europace. 2023 Feb 16;25(2):676-681. doi: 10.1093/europace/euac194.
9
Management of atrial fibrillation in patients with chronic kidney disease in clinical practice: a joint European Heart Rhythm Association (EHRA) and European Renal Association/European Dialysis and Transplantation Association (ERA/EDTA) physician-based survey.临床实践中慢性肾脏病患者心房颤动的管理:一项基于医师的联合欧洲心律协会(EHRA)和欧洲肾脏协会/欧洲透析和移植协会(ERA/EDTA)的调查。
Europace. 2020 Mar 1;22(3):496-505. doi: 10.1093/europace/euz358.
10
Management of atrial fibrillation in patients with chronic kidney disease in Europe Results of the European Heart Rhythm Association Survey.在欧洲,慢性肾脏病患者的心房颤动管理——来自欧洲心律协会调查的结果。
Europace. 2015 Dec;17(12):1862-7. doi: 10.1093/europace/euv416.

引用本文的文献

1
Arrhythmia care in ESC member countries: the 2025 ESC-EHRA atlas on heart rhythm disorders.欧洲心脏病学会成员国的心律失常护理:2025年欧洲心脏病学会-欧洲心律协会心律紊乱图谱
Europace. 2025 Jul 1;27(7). doi: 10.1093/europace/euaf124.
2
Educating healthcare professionals to improve AF-CARE: lessons from the ESC/EHRA STEEER-AF trial educational programme.教育医疗保健专业人员以改善房颤护理:欧洲心脏病学会/欧洲心律协会STEEER-AF试验教育项目的经验教训。
Europace. 2025 Jul 1;27(7). doi: 10.1093/europace/euaf142.
3
Antiarrhythmic drug use in atrial fibrillation among different European countries - as determined by a physician survey.

本文引用的文献

1
Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes.在伴有心房快速发作的患者中使用依度沙班进行抗凝治疗。
N Engl J Med. 2023 Sep 28;389(13):1167-1179. doi: 10.1056/NEJMoa2303062. Epub 2023 Aug 25.
2
EUropean real-world outcomes with Pulsed field ablatiOn in patients with symptomatic atRIAl fibrillation: lessons from the multi-centre EU-PORIA registry.脉冲场消融治疗有症状心房颤动患者的欧洲真实世界结局:来自多中心 EU-PORIA 注册研究的经验。
Europace. 2023 Jul 4;25(7). doi: 10.1093/europace/euad185.
3
The scale of scientific evidence behind the current ESC clinical guidelines.
不同欧洲国家心房颤动患者抗心律失常药物的使用情况——基于一项医师调查的结果
Int J Cardiol Heart Vasc. 2025 May 31;59:101709. doi: 10.1016/j.ijcha.2025.101709. eCollection 2025 Aug.
4
Towards personalized therapy for atrial fibrillation: the rhythmic climbing of dronedarone.迈向心房颤动的个性化治疗:决奈达隆的节律性攀升。
Europace. 2025 Mar 28;27(4). doi: 10.1093/europace/euaf079.
5
Artificial Intelligence in Atrial Fibrillation: From Early Detection to Precision Therapy.心房颤动中的人工智能:从早期检测到精准治疗
J Clin Med. 2025 Apr 11;14(8):2627. doi: 10.3390/jcm14082627.
6
Flecainide and atrial fibrillation cardioversion: what solutions at present and in the near future?氟卡尼与心房颤动复律:目前及近期有哪些解决方案?
Europace. 2025 Mar 28;27(4). doi: 10.1093/europace/euaf063.
7
Practical Compendium of Antiarrhythmic Drugs: A Clinical Consensus Statement of the European Heart Rhythm Association of the ESC.抗心律失常药物实用手册:欧洲心脏病学会(ESC)欧洲心律协会临床共识声明
Europace. 2025 Mar 30. doi: 10.1093/europace/euaf076.
8
Persistent atrial fibrillation ablation: glimpsing the light ahead?持续性心房颤动消融术:曙光在望?
Europace. 2025 Jun 3;27(6). doi: 10.1093/europace/euaf037.
9
Defining myocardial fiber bundle architecture in atrial digital twins.定义心房数字孪生模型中的心肌纤维束结构
Comput Biol Med. 2025 Apr;188:109774. doi: 10.1016/j.compbiomed.2025.109774. Epub 2025 Feb 12.
10
Spotlight on the 2024 ESC/EACTS management of atrial fibrillation guidelines: 10 novel key aspects.聚焦2024年欧洲心脏病学会/欧洲心胸外科学会心房颤动管理指南:10个新的关键方面。
Europace. 2024 Dec 3;26(12). doi: 10.1093/europace/euae298.
当前欧洲心脏病学会临床指南背后的科学证据规模。
Int J Cardiol Heart Vasc. 2023 Jan 17;45:101175. doi: 10.1016/j.ijcha.2023.101175. eCollection 2023 Apr.
4
Patient selection, peri-procedural management, and ablation techniques for catheter ablation of atrial fibrillation: an EHRA survey.经导管消融治疗心房颤动的患者选择、围术期管理和消融技术:EHRA 调查。
Europace. 2023 Feb 16;25(2):667-675. doi: 10.1093/europace/euac236.
5
Antithrombotic therapy for stroke prevention in patients with atrial fibrillation who survive an intracerebral haemorrhage: results of an EHRA survey.心房颤动患者脑出血存活者的卒中预防的抗血栓治疗:EHRA 调查结果。
Europace. 2021 May 21;23(5):806-814. doi: 10.1093/europace/euaa423.
6
Catheter ablation or medical therapy to delay progression of atrial fibrillation: the randomized controlled atrial fibrillation progression trial (ATTEST).导管消融或药物治疗延缓心房颤动进展:随机对照心房颤动进展试验(ATTEST)。
Europace. 2021 Mar 8;23(3):362-369. doi: 10.1093/europace/euaa298.
7
Early Rhythm-Control Therapy in Patients with Atrial Fibrillation.心房颤动患者的早期节律控制治疗。
N Engl J Med. 2020 Oct 1;383(14):1305-1316. doi: 10.1056/NEJMoa2019422. Epub 2020 Aug 29.
8
2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC.2020年欧洲心脏病学会(ESC)与欧洲心胸外科学会(EACTS)合作制定的心房颤动诊断和管理指南:欧洲心脏病学会(ESC)心房颤动诊断和管理特别工作组,由ESC欧洲心律协会(EHRA)特别贡献制定。
Eur Heart J. 2021 Feb 1;42(5):373-498. doi: 10.1093/eurheartj/ehaa612.
9
Wrist band photoplethysmography in detection of individual pulses in atrial fibrillation and algorithm-based detection of atrial fibrillation.腕带光电容积脉搏波描记法检测心房颤动中的个体脉搏和基于算法的心房颤动检测。
Europace. 2019 Jul 1;21(7):1031-1038. doi: 10.1093/europace/euz060.
10
Direct Oral Anticoagulants in Patients With Atrial Fibrillation and Liver Disease.直接口服抗凝剂在房颤合并肝病患者中的应用。
J Am Coll Cardiol. 2019 Jul 2;73(25):3295-3308. doi: 10.1016/j.jacc.2019.04.052.