Department of Cardiology, Hospital de la Santa Creu i Sant Pau, IR SANT PAU, Universitat Autònoma de Barcelona, CIBERCV, Sant Antoni M. Claret 167, 08025 Barcelona, Spain.
Arrhythmia Unit, Careggi University Hospital, Florence, Italy.
Europace. 2024 Feb 1;26(2). doi: 10.1093/europace/euae012.
Although guidelines for the management of atrial fibrillation (AF) are regularly published, many controversial issues remain, limiting their implementation. We aim to describe current clinical practice among European Heart Rhythm Association (EHRA) community according to last guidelines.
A 30 multiple-choice questionnaire covering the most controversial topics related to AF management was distributed through the EHRA Research Network, National Societies, and social media between January and February 2023. One hundred and eighty-one physicians responded the survey, 61% from university hospitals. Atrial fibrillation screening in high-risk patients is regularly performed by 57%. Only 42% has access to at least one programme aiming at diagnosing/managing comorbidities and lifestyle modifications, with marked heterogeneity between countries. Direct oral anticoagulants are the preferred antithrombotic (97%). Rhythm control is the preferred strategy in most AF phenotypes: symptomatic vs. asymptomatic paroxysmal AF (97% vs. 77%), low vs. high risk for recurrence persistent AF (90% vs. 72%), and permanent AF (20%). I-C drugs and amiodarone are preferred while dronedarone and sotalol barely used. Ablation is the first-line therapy for symptomatic paroxysmal AF (69%) and persistent AF with markers of atrial disease (57%) and is performed independently of symptoms by 15%. In persistent AF, 68% performs only pulmonary vein isolation and 32% also additional lesions.
There is marked heterogeneity in AF management and limited accordance to last guidelines in the EHRA community. Most of the discrepancies are related to the main controversial issues, such as those related to AF screening, management of comorbidities, pharmacological treatment, and ablation strategy.
尽管已经定期发布了心房颤动(AF)管理指南,但仍存在许多有争议的问题,限制了其实施。我们旨在根据最新指南描述欧洲心律协会(EHRA)社区当前的临床实践。
在 2023 年 1 月至 2 月期间,通过 EHRA 研究网络、国家协会和社交媒体,向 181 名医生分发了一份涵盖与 AF 管理最相关的 30 个多项选择题的调查问卷。61%的应答者来自大学医院。57%的医生定期对高危患者进行房颤筛查。只有 42%的医生可以获得至少一个旨在诊断/管理合并症和生活方式改变的项目,各国之间存在明显的差异。直接口服抗凝剂是首选的抗血栓药物(97%)。在大多数 AF 表型中,节律控制是首选策略:症状性与无症状阵发性 AF(97%与 77%)、低复发风险与高复发风险持续性 AF(90%与 72%)、永久性 AF(20%)。I-C 类药物和胺碘酮是首选药物,而多非利特和索他洛尔很少使用。消融是症状性阵发性 AF(69%)和有房性疾病标志物的持续性 AF(57%)的一线治疗方法,15%的医生在没有症状的情况下进行消融。在持续性 AF 中,68%的医生仅进行肺静脉隔离,32%的医生还进行额外的消融。
EHRA 社区在 AF 管理方面存在明显的异质性,且与最新指南的一致性有限。大多数差异与主要的争议问题有关,例如与 AF 筛查、合并症管理、药物治疗和消融策略有关。