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[2000 - 2019年中国青少年结核病流行趋势]

[Epidemic trend of tuberculosis in adolescents in China, 2000-2019].

作者信息

Shang W J, Liu M

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2024 Jan 10;45(1):78-86. doi: 10.3760/cma.j.cn112338-20230726-00043.

Abstract

To analyze the epidemic trend of tuberculosis (TB) in adolescents in China from 2000 to 2019. We used data from Global Burden of Disease Study 2019 to describe the epidemic trend of TB. The estimated annual percentage changes (EAPC) of the morbidity and mortality were calculated to assess epidemic trends from 2000 to 2019. In 2019, a total of 37 815.670 TB cases and 213.629 deaths were reported in adolescents in China, the morbidity was 25.938/100 000 and the mortality was 0.147/100 000. The cases and deaths of TB in 2019 decreased by 71.84% and 89.90% respectively compared with 2000. In 2019, the incident case number (21 371.747) was 1.30 times higher in male adolescents than in female adolescents (16 443.923), and was 4.11 times higher in age group 15-19 years (30 420.054) than in age group 10-14 years (7 395.616). From 2000 to 2019, the morbidity (EAPC=-3.95, 95%: -4.34- -3.55) and mortality (EAPC=-9.18, 95%: -9.33- -9.02) of TB in the adolescents showed decreasing trends. The morbidity and mortality of drug-sensitive TB, extensively drug-resistant TB and multidrug-resistant TB all showed decreasing trends. The morbidity and mortality of TB and its subtypes among adolescents in China decreased during 2000-2019. More attention should be paid to male adolescents and adolescents aged 15-19 years due to relatively higher incidence intensity of TB.

摘要

分析2000年至2019年中国青少年结核病(TB)的流行趋势。我们使用了《2019年全球疾病负担研究》的数据来描述结核病的流行趋势。计算发病率和死亡率的估计年百分比变化(EAPC)以评估2000年至2019年的流行趋势。2019年,中国青少年共报告37815.670例结核病病例和213.629例死亡,发病率为25.938/10万,死亡率为0.147/10万。与2000年相比,2019年结核病病例数和死亡数分别下降了71.84%和89.90%。2019年,男性青少年的发病例数(21371.747)比女性青少年(16443.923)高1.30倍,在15 - 19岁年龄组(30420.054)比10 - 14岁年龄组(7395.616)高4.11倍。2000年至2019年,青少年结核病的发病率(EAPC = -3.95,95%:-4.34 - -3.55)和死亡率(EAPC = -9.18,95%:-9.33 - -9.02)呈下降趋势。药敏结核病、广泛耐药结核病和耐多药结核病的发病率和死亡率均呈下降趋势。2000 - 2019年期间,中国青少年结核病及其亚型的发病率和死亡率下降。由于结核病发病强度相对较高,应更多关注男性青少年和15 - 19岁的青少年。

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