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[1990 - 2017年中国结核病流行特征及防控状况描述]

[Description of epidemic features and control status on tuberculosis in China, 1990-2017].

作者信息

Wang X J, Li Y H, Yi F L, Fu Q

机构信息

Wuhan Institute for Tuberculosis Control, Wuhan Pulmonary Hospital, Wuhan 430030, China.

School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Jun 10;41(6):856-860. doi: 10.3760/cma.j.cn112338-20190809-00587.

Abstract

To analyse the epidemic features and programs of control on tuberculosis (TB) in China from 1990 to 2017 to provide references and evidence on prevention and control of the disease. We used data from the Global Burden of Disease Study 2017 to analyse the trends of incident and death cases of TB in China from 1990 to 2017. In 2017, there were an estimated 831.0 thousand (age-standardized incidence: 54.18 per 100 000 population) incident cases and 39.3 thousand (age-standardised mortality: 2.17 per 100 000 population) deaths of TB in the country. The incident cases and deaths of TB decreased by 51.05 and 76.24 compared with the numbers in 1990, respectively. The average annual declining rates on incident cases and deaths of TB were 2.61 and 5.18, respectively, from 1990 to 2017. The number of incident cases of TB decreased from 833.6 thousand in 2016 to 831.0 thousand in 2017 (decreased by 0.31). The number of deaths of TB decreased from 40.7 thousand in 2016 to 39.3 thousand in 2017 (decreased by 3.44). The number of incident cases and deaths of drug-sensitive TB showed a declining trend from 1990 to 2017. However, the number of incident cases and deaths showed first increased and then decreased trends for both multidrug-resistant TB (MDRTB) and extensively drug-resistant TB (XDRTB) in the same period. The number of incident cases of XDRTB increased from 2 979 in 2016 to 3 018 in 2017, with an increasing rate by 1.32. The number of deaths of XDRTB increased from 819 in 2016 to 829 in 2017, with an increase rate by 1.22. China made substantial progress in reducing both the TB incidence and mortality from 1990 to 2017 but the rate of decline became slow in the later years. We noticed that the increase of TB caused by XDR-TB had been increasing which called for special attention.

摘要

分析1990年至2017年中国结核病的流行特征及防控方案,为该病的预防和控制提供参考依据和证据。我们使用了《2017年全球疾病负担研究》的数据来分析1990年至2017年中国结核病发病和死亡病例的趋势。2017年,全国估计有83.1万例结核病发病病例(年龄标准化发病率:每10万人中54.18例)和3.93万例死亡病例(年龄标准化死亡率:每10万人中2.17例)。与1990年相比,结核病发病病例和死亡病例分别下降了51.05%和76.24%。1990年至2017年,结核病发病病例和死亡病例的年均下降率分别为2.61%和5.18%。结核病发病病例数从2016年的83.36万例降至2017年的83.1万例(下降了0.31%)。结核病死亡病例数从2016年的4.07万例降至2017年的3.93万例(下降了3.44%)。1990年至2017年,敏感结核病的发病病例数和死亡病例数呈下降趋势。然而,同期耐多药结核病(MDRTB)和广泛耐药结核病(XDRTB)的发病病例数和死亡病例数均呈先上升后下降趋势。广泛耐药结核病的发病病例数从2016年的2979例增至2017年的3018例,增长率为1.32%。广泛耐药结核病的死亡病例数从2016年的819例增至2017年的829例,增长率为1.22%。1990年至2017年,中国在降低结核病发病率和死亡率方面取得了显著进展,但后期下降速度放缓。我们注意到,由广泛耐药结核病导致的结核病病例数一直在增加,这需要特别关注。

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