Morrice Marcelo, Wilner Andrew
The University of Tennessee Health Science Center College of Medicine, Memphis, TN, USA.
University of Tennessee Health Science Center, Memphis, TN, USA.
Neurohospitalist. 2024 Jan;14(1):106-109. doi: 10.1177/19418744231204103. Epub 2023 Sep 22.
A previously healthy 21-year-old Caucasian female G1P0 at 32 weeks gestation presented to the ED for an episode of syncope. She also complained of headaches, neck pain, and blurry vision. Physical examination revealed a healthy pregnant female. Neurological examination demonstrated Grade III papilledema but was otherwise unremarkable. CT brain revealed hydrocephalus and intraventricular hemorrhage of unclear etiology MRI of the head was negative for a mass lesion. MRA/MRV of the head was negative, ruling out cavernous sinus thrombosis. Lumbar puncture was bloody but negative for infection. Infectious workup, including HSV, toxoplasmosis, and neurocysticercosis, was negative. An intraventricular drain was placed for hydrocephalus. While in the hospital, she developed sudden left-sided weakness, prompting an emergency C-section. Further workup with CT angio of the brain and neck revealed an arteriovenous malformation (AVM) involving the anterior spinal artery and adjacent venous plexus. Digital subtraction angiography showed a C2-3 pial AVM with a partially thrombosed nidal aneurysm. She was transferred to an outside hospital for embolization. Embolization obliterated the aneurysm, but residual flow remained in the AVM. Blood products are visible on sagittal MRI after embolization. At hospital discharge, her left-sided weakness had resolved, and her neurological examination was normal. The hydrocephalus had resolved.
一名既往健康的21岁白种人女性,孕32周,G1P0,因晕厥发作就诊于急诊科。她还主诉头痛、颈部疼痛和视力模糊。体格检查显示为一名健康的孕妇。神经系统检查发现III级视乳头水肿,其他方面无异常。头颅CT显示脑积水和病因不明的脑室内出血,头颅MRI未发现占位性病变。头颅MRA/MRV检查结果为阴性,排除海绵窦血栓形成。腰椎穿刺脑脊液呈血性,但感染检查为阴性。包括单纯疱疹病毒、弓形虫病和神经囊尾蚴病在内的感染性检查均为阴性。因脑积水放置了脑室内引流管。住院期间,她突然出现左侧肢体无力,遂紧急行剖宫产。脑部和颈部CT血管造影进一步检查发现一个动静脉畸形(AVM),累及脊髓前动脉和相邻的静脉丛。数字减影血管造影显示C2 - 3软膜动静脉畸形,伴有部分血栓形成的巢状动脉瘤。她被转至外院进行栓塞治疗。栓塞治疗使动脉瘤闭塞,但动静脉畸形仍有残余血流。栓塞治疗后矢状位MRI可见血液成分。出院时,她左侧肢体无力已缓解,神经系统检查正常。脑积水也已消退。