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死于新生幼犬衰竭综合征的幼犬的肺表面活性物质组成

Lung surfactant composition in puppies dying of fading puppy complex.

作者信息

Blunden A S, Hill C M, Brown B D, Morley C J

出版信息

Res Vet Sci. 1987 Jan;42(1):113-8.

PMID:3823624
Abstract

The composition of surfactant from the lungs of neonatal puppies dying from 'fadding puppy complex' differs from that of neonates dying from other causes. Surfactant from 'fading puppies' contained significantly less phosphatidylcholine than did the surfactant from other puppies, and therefore abnormal surfactant may be implicated in fading puppy complex. Abnormal surfactant has been implicated in the pathogenesis of sudden infant death syndrome in human infants.

摘要

死于“幼犬衰弱综合征”的新生幼犬肺部表面活性剂的成分与死于其他原因的新生儿的不同。“衰弱幼犬”的表面活性剂所含磷脂酰胆碱明显少于其他幼犬的表面活性剂,因此异常表面活性剂可能与幼犬衰弱综合征有关。异常表面活性剂与人类婴儿猝死综合征的发病机制有关。

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