Department of Automation, University of Science and Technology of China, Hefei, People's Republic of China.
School of Cyber Science and Technology, University of Science and Technology of China, Hefei, People's Republic of China.
Phys Med Biol. 2024 Feb 5;69(4). doi: 10.1088/1361-6560/ad2013.
Recent developments in x-ray image based pulmonary nodule detection have achieved remarkable results. However, existing methods are focused on transferring off-the-shelf coarse-grained classification models and fine-grained detection models rather than developing a dedicated framework optimized for nodule detection. In this paper, we propose PN-DetX, which as we know is the first dedicated pulmonary nodule detection framework. PN-DetX incorporates feature fusion and self-attention into x-ray based pulmonary nodule detection tasks, achieving improved detection performance. Specifically, PN-DetX adopts CSPDarknet backbone to extract features, and utilizes feature augmentation module to fuse features from different levels followed by context aggregation module to aggregate semantic information. To evaluate the efficacy of our method, we collect arge-scaleulmonaryduleetection dataset,, comprising 2954 x-ray images along with expert-annotated ground truths. As we know, this is the first large-scale chest x-ray pulmonary nodule detection dataset. Experiments demonstrates that our method outperforms baseline by 3.8% mAP and 5.1%. The generality of our approach is also evaluated on the publicly available dataset NODE21. We aspire for our method to serve as an inspiration for future research in the field of pulmonary nodule detection. The dataset and codes will be made in public.
基于 X 射线图像的肺结节检测的最新进展已经取得了显著的成果。然而,现有的方法主要集中在转移现成的粗粒度分类模型和细粒度检测模型,而不是开发专门针对结节检测的优化框架。在本文中,我们提出了 PN-DetX,据我们所知,这是第一个专门用于肺结节检测的框架。PN-DetX 将特征融合和自注意力纳入基于 X 射线的肺结节检测任务中,实现了更好的检测性能。具体来说,PN-DetX 采用 CSPDarknet 骨干网络提取特征,并利用特征增强模块融合来自不同层次的特征,然后利用上下文聚合模块聚合语义信息。为了评估我们方法的效果,我们收集了一个大规模的肺结节检测数据集,包含 2954 张 X 射线图像和专家标注的地面真实数据。据我们所知,这是第一个大规模的胸部 X 射线肺结节检测数据集。实验表明,我们的方法在 mAP 和 5.1%的指标上比基线提高了 3.8%。我们还在公开数据集 NODE21 上评估了我们方法的通用性。我们希望我们的方法能够为肺结节检测领域的未来研究提供灵感。数据集和代码将公开发布。