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一例与鸟分枝杆菌相关的非典型抗肾小球基底膜肾炎病例报告。

A case report of atypical anti-glomerular basement membrane nephritis associated with Mycobacterium Avium.

作者信息

Bech Jensen Julie, Gravesen Eva, Graff Jensen Sidse, Bressendorff Iain

机构信息

Department of Nephrology.

Department of Pathology, and.

出版信息

Clin Nephrol Case Stud. 2024 Jan 12;12:12-16. doi: 10.5414/CNCS111254. eCollection 2024.

Abstract

We present the case of a woman with atypical anti-glomerular basement membrane (anti-GBM) nephritis associated with concurrent pulmonary infection with . A kidney biopsy showed crescentic glomerulonephritis with 50% active crescents and linear IgG staining, but no circulating anti-GBM antibodies were detected, and the patient did not have pulmonary hemorrhage. Despite treatment with a triple-regimen of antibiotics, corticosteroids, and plasmapheresis, the patient did not regain kidney function. One year later she is on maintenance dialysis and has still not cleared the infection with .

摘要

我们报告了一例患有非典型抗肾小球基底膜(anti-GBM)肾炎并同时合并肺部感染的女性病例。肾活检显示为新月体性肾小球肾炎,有50%的活动性新月体和线性IgG染色,但未检测到循环抗GBM抗体,且患者没有肺出血。尽管采用了抗生素、皮质类固醇和血浆置换三联疗法进行治疗,患者的肾功能仍未恢复。一年后,她接受维持性透析,肺部感染仍未清除。

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