Bech Jensen Julie, Gravesen Eva, Graff Jensen Sidse, Bressendorff Iain
Department of Nephrology.
Department of Pathology, and.
Clin Nephrol Case Stud. 2024 Jan 12;12:12-16. doi: 10.5414/CNCS111254. eCollection 2024.
We present the case of a woman with atypical anti-glomerular basement membrane (anti-GBM) nephritis associated with concurrent pulmonary infection with . A kidney biopsy showed crescentic glomerulonephritis with 50% active crescents and linear IgG staining, but no circulating anti-GBM antibodies were detected, and the patient did not have pulmonary hemorrhage. Despite treatment with a triple-regimen of antibiotics, corticosteroids, and plasmapheresis, the patient did not regain kidney function. One year later she is on maintenance dialysis and has still not cleared the infection with .
我们报告了一例患有非典型抗肾小球基底膜(anti-GBM)肾炎并同时合并肺部感染的女性病例。肾活检显示为新月体性肾小球肾炎,有50%的活动性新月体和线性IgG染色,但未检测到循环抗GBM抗体,且患者没有肺出血。尽管采用了抗生素、皮质类固醇和血浆置换三联疗法进行治疗,患者的肾功能仍未恢复。一年后,她接受维持性透析,肺部感染仍未清除。