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缩小差距:一例脑脊液漏血补丁解决方案的病例报告

Closing the Gap: A Case Report on a Blood Patch Solution for Cerebrospinal Fluid Leak.

作者信息

Sousa Guilherme, Alves Bárbara, Cunha Filipa, Magalhães Juliana, Figueiredo Eduarda, Abreu Luís

机构信息

Anaesthesiology, Centro Hospitalar Tondela-Viseu, Viseu, PRT.

Neurology, Centro Hospitalar Tondela-Viseu, Viseu, PRT.

出版信息

Cureus. 2023 Dec 19;15(12):e50784. doi: 10.7759/cureus.50784. eCollection 2023 Dec.

Abstract

Spontaneous intracranial hypotension is a condition resulting from cerebrospinal fluid leaks at the spinal level that disrupt the regulation of intracranial pressure. This disorder is an uncommon cause of debilitating headaches but can have variable clinical manifestations, which contributes to delayed diagnosis and potentially severe consequences. The standard treatment consists of conservative measures such as bed rest, hydration, and a pharmacological approach with paracetamol, caffeine, ergotamine, and dexamethasone. When conservative measures fail, an epidural blood patch is the gold standard treatment, where a small amount of blood is injected into the epidural space to form a clot to seal any existing leak. Recent studies showed a success rate of 64% without the need for further intervention. The authors report a case of a 55-year-old woman with a three-month history of daily severe headaches. Imaging exams showed subdural collections, suggesting the hypothesis of cerebrospinal fluid hypotension. After the failure of conservative measures, an epidural blood patch was performed with progressive clinical improvement.  This case demonstrates the potential effectiveness of an epidural blood patch in the management of spontaneous intracranial hypotension and its complications, offering an encouraging option for those unresponsive to conservative measures. It also highlights the importance of a multidisciplinary approach involving neurologists and anesthesiologists.

摘要

自发性颅内低压是一种由于脊髓水平脑脊液漏导致颅内压调节紊乱的病症。这种疾病是导致使人衰弱的头痛的罕见原因,但临床表现可能多种多样,这导致诊断延迟并可能产生严重后果。标准治疗包括保守措施,如卧床休息、补液,以及使用对乙酰氨基酚、咖啡因、麦角胺和地塞米松的药物治疗方法。当保守措施失败时,硬膜外血贴是金标准治疗方法,即向硬膜外间隙注入少量血液以形成凝块来封闭任何现有的漏口。最近的研究表明,无需进一步干预的成功率为64%。作者报告了一例55岁女性,有三个月每日严重头痛的病史。影像学检查显示硬膜下积液,提示脑脊液低压的假说。保守措施失败后,进行了硬膜外血贴,临床症状逐渐改善。该病例证明了硬膜外血贴在自发性颅内低压及其并发症管理中的潜在有效性,为那些对保守措施无反应的患者提供了一个令人鼓舞的选择。它还强调了涉及神经科医生和麻醉科医生的多学科方法的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43a/10795794/733cf2fb4571/cureus-0015-00000050784-i01.jpg

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