Centre for Nanobiotechnology, Vellore Institute of Technology, Vellore, 632014, Tamil Nadu, India.
Environ Sci Pollut Res Int. 2024 Feb;31(9):13207-13217. doi: 10.1007/s11356-024-31998-8. Epub 2024 Jan 19.
The increasing use of polypropylene (PP) in consumer products leads to the microplastic (PP MPs) contamination of the aquatic ecosystems. Comprehensive toxicological studies of weathered/aged and new PP MPs with Artemia salina are a need of the hour. Our study explores the toxicological differences between naturally weathered (aged) and prepared new PP MPs on Artemia salina. Both the weathered and new PP MPs were prepared using controlled grinding and sieving at ≤ 125 µm. Artemia salina was treated with different concentrations (0.25, 0.5, and 1 mg/mL) of PP MP particles for up to 48 h. The uptake of weathered PP MP particles by Artemia salina was higher than the new PP MPs. The accumulation of PP MP particles was found in the intestine. There was increased oxidative stress recorded in the animal treated with the weathered PP MPs than the new PP MPs. Artemia salina treated with weathered PP MPs showed higher ROS generation and increased, activity of oxidative enzymes like LPO, SOD, and CAT. Collectively, our findings underscore the detrimental effects of weathered and prepared new PP MPs on Artemia salina, which is an ecologically significant species of zooplankton. There is an urgent need and effective measures required to address plastic disposal strategies in an environmentally safe manner.
聚丙烯（PP）在消费品中的应用日益广泛，导致微塑料（PP MPs）污染水生生态系统。迫切需要对经过风化/老化和新的 PP MPs 与卤虫进行综合毒理学研究。我们的研究探讨了天然风化（老化）和制备的新 PP MPs 对卤虫的毒理学差异。风化和新的 PP MPs 均使用受控研磨和≤125μm 的筛分制备。用不同浓度（0.25、0.5 和 1mg/mL）的 PP MP 颗粒处理卤虫，时间长达 48 小时。卤虫对风化 PP MP 颗粒的摄取量高于新的 PP MPs。在经风化的 PP MPs 处理的动物中发现 PP MP 颗粒的积累在肠道中。与新的 PP MPs 相比，用风化的 PP MPs 处理的动物记录到的氧化应激增加。用风化的 PP MPs 处理的卤虫显示出更高的 ROS 生成和增加的氧化酶活性，如 LPO、SOD 和 CAT。总的来说，我们的研究结果强调了风化和制备的新 PP MPs 对卤虫的有害影响，卤虫是一种具有重要生态意义的浮游动物。迫切需要采取有效措施，以环境安全的方式解决塑料处理策略。
