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研究合成亮片对卤虫的毒性及生物放大潜力。

Investigating on the toxicity and bio-magnification potential of synthetic glitters on Artemia salina.

作者信息

Das Pramanik Devlina, Lei Sihan, Kay Paul, Goycoolea Francisco M

机构信息

School of Food Science and Nutrition, Faculty of Environment, University of Leeds, LS29JT, United Kingdom; Centre for Biotechnology and Biochemical Engineering, Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh 201301, India.

School of Food Science and Nutrition, Faculty of Environment, University of Leeds, LS29JT, United Kingdom.

出版信息

Mar Pollut Bull. 2023 May;190:114828. doi: 10.1016/j.marpolbul.2023.114828. Epub 2023 Mar 16.

Abstract

Our research aims to assess the toxic impacts of polyethylene terephthalate (PET) glitters on Artemia salina as a model zooplankton. The mortality rate was assessed using a Kaplan Maier plot as a function of various microplastic dosages. The ingestion of microplastics was confirmed by their presence in digestive tract and faecal matter. Gut wall damage was confirmed by dissolution of basal lamina walls and an increase in the secretory cells. A significant decrease in the activities of cholinesterase (ChE) and glutathione-S-transferase (GST) were noted. A decrease in catalase activity could be correlated to an increase in the generation of reactive oxygen species (ROS). Cysts incubated in presence of microplastics exhibited delay in their hatching into 'umbrella' and 'instar' stages. The data presented in the study would be useful for scientists working on discovering new sources of microplastics, related scientific evidences, image data and model of study.

摘要

我们的研究旨在评估聚对苯二甲酸乙二酯(PET)亮片作为一种模型浮游动物对卤虫的毒性影响。使用Kaplan Maier图评估死亡率与各种微塑料剂量的函数关系。微塑料在消化道和粪便中的存在证实了其被摄入。通过基底层壁的溶解和分泌细胞的增加证实了肠壁损伤。注意到胆碱酯酶(ChE)和谷胱甘肽-S-转移酶(GST)的活性显著降低。过氧化氢酶活性的降低可能与活性氧(ROS)生成的增加相关。在微塑料存在下孵化的囊肿在孵化成“伞状”和“龄期”阶段时出现延迟。该研究中呈现的数据将有助于致力于发现微塑料新来源、相关科学证据、图像数据和研究模型的科学家。

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