Koshlia V I
Ter Arkh. 1986;58(11):51-5.
Corvaton treatment of 23 patients with congestive heart failure caused by rheumatic valvular heart diseases, continued for 10 mos. An increase in the stroke and minute blood volume in the chest, leg and fingers, and a decrease in the peripheral vascular resistance and systolic pressure in the pulmonary artery were noted as a result of corvaton therapy. Corvaton efficacy was assessed by change in hemodynamics for 2 h after administration of the drug at a single dose of 4 mg. A response of hemodynamics to corvaton was preserved for 10 mos.
用Corvaton治疗23例风湿性瓣膜性心脏病所致充血性心力衰竭患者，持续10个月。结果显示，Corvaton治疗后胸部、腿部和手指的每搏输出量和每分钟血流量增加，外周血管阻力和肺动脉收缩压降低。通过单次静脉注射4mg药物后2小时血流动力学的变化来评估Corvaton的疗效。血流动力学对Corvaton的反应持续了10个月。
