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儿童中度烧伤的伤口感染——报告频率与诊断之间关联的探索性综述。

Wound infection among children with moderate burns - An explorative review of the association between reported frequency and diagnosis.

机构信息

Department of Hand Surgery, Plastic Surgery and Burns, Linköping, Sweden; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden; Department of Infectious Diseases, Östergötland, Sweden.

出版信息

Burns. 2024 Apr;50(3):742-753. doi: 10.1016/j.burns.2023.12.008. Epub 2023 Dec 22.

Abstract

INTRODUCTION

The Linkoping burn centre in Sweden has, even though being a high income country, reported high burn wound infections (BWI) frequencies in scalded children compared to similar populations in other parts of the world.

AIM

The aim was to investigate possible explanations for differences in frequency of BWI among children with partial thickness burns treated at the Linköping burn centre in Sweden, and that reported in other studies.

METHOD

In order to investigate what BWI criteria that were used in similar studies a literature search on PubMed Central was done along with a retrospective analysis of children previously diagnosed as infected to confirm or reject the high infection frequency reported earlier.

RESULT

Of the 34 selected publications reporting on BWI frequency 16 (47%) did not define a criteria for the BWI diagnosis and almost a third did not report on wound culturing. Of those who did report the use a third do not mention any bacterial growth found is these cultures. The retrospective analysis on children at the centre did not show any decrease in infection frequency even with some disagreement on onset for the BWI.

CONCLUSION

The reporting of criteria and diagnosis of burn wound infection is highly variable making it difficult to interpret results and come to conclusions. The high frequency of BWI at the centre might be a result of close monitoring due to study participation, use of clean instead of sterile routine at dressing changes or low thresholds for the diagnosis in respect to changes in infection markers.

摘要

引言

瑞典林雪平烧伤中心尽管属于高收入国家,但与世界其他地区类似人群相比,报告的烫伤儿童烧伤创面感染(BWI)频率较高。

目的

旨在探讨瑞典林雪平烧伤中心治疗的部分厚度烧伤儿童与其他研究报告的 BWI 频率差异的可能原因。

方法

为了调查在类似研究中使用的 BWI 标准,在 PubMed Central 上进行了文献检索,并对以前诊断为感染的儿童进行了回顾性分析,以确认或否定之前报告的高感染频率。

结果

在 34 篇报告 BWI 频率的选定出版物中,16 篇(47%)未定义 BWI 诊断标准,近三分之一未报告伤口培养。在报告使用标准的那些人中,有三分之一没有提到这些培养物中发现的任何细菌生长。中心对儿童的回顾性分析并未显示感染频率降低,即使在 BWI 的发病时间上存在一些分歧。

结论

烧伤创面感染的报告标准和诊断高度可变,使得难以解释结果并得出结论。该中心 BWI 频率较高可能是由于参与研究导致的密切监测、在更换敷料时使用清洁而非无菌常规、或在感染标志物变化时诊断的门槛较低所致。

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