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脉搏血氧饱和度测定法在全膝关节置换术后早期诊断肺栓塞中的有效性。

Efficacy of pulse oximetry for early diagnosis of pulmonary embolism after total knee arthroplasty.

作者信息

Yoo Ju-Hyung, Park Sang-Hoon, Oh Hyun-Cheol, Ha Joong-Won, Yoon Han-Kook

机构信息

Department of Orthopedic Surgery, National Health Insurance Service Ilsan Hospital, Ilsan-ro 100, Ilsandong-gu, Goyang, 10444, South Korea.

Department of Orthopedic Surgery, Seran Hospital, Seoul, Korea.

出版信息

Knee Surg Relat Res. 2024 Jan 21;36(1):6. doi: 10.1186/s43019-023-00207-0.

Abstract

INTRODUCTION

Early diagnosis and aggressive treatment of pulmonary embolism (PE) are crucial for preventing severe complications after total knee arthroplasty (TKA). This study aimed to examine the efficacy of measuring oxygen saturation (SpO) using a pulse oximeter for early diagnosis of PE after total knee arthroplasty (TKA).

MATERIALS AND METHODS

We consecutively examined 1645 patients who underwent TKA between January 2015 and November 2019. Postoperative SpO was measured with a pulse oximeter, which was stopped if SpO was maintained at ≥ 95% until postoperative day 2 (POD2). To diagnose PE, computed tomographic pulmonary angiography (CTPA) was performed for specific indications, including persistently low SpO < 95% (group 1), sudden decrease in SpO (group 2), and decrease in SpO after POD3 with presenting symptoms (group 3). Also, we divided the patients into unilateral, simultaneous and sequential TKA groups and compared the results with specific statistical techniques.

RESULTS

Of the 1645 patients who underwent TKA, there were 20 patients with PE (1.2%), and symptomatic PE was observed in only 4 patients (0.24%). CTPA was performed in 58 (3.5%) patients, of whom 20 were diagnosed with PE. In groups 1 (n = 34), 2 (n = 21), and 3 (n = 3), CTPA was performed 2.4, 2.6, and 8.3 days after TKA, respectively, and 12, 8, and 0 patients were diagnosed with PE, respectively. Of the 782, 416, and 447 unilateral, simultaneous, and sequential (done in same admission with interval 1 or 2 weeks) patients with TKA, 38, 18, and 2 received CTPA, and 13, 6, and 1 were diagnosed with PE, respectively. All patients diagnosed with PE have persistently low SpO < 95% (group 1), or sudden decrease in SpO2 (group 2) until POD2. Of the patients diagnosed with PE, SpO decreased without the presentation of symptoms in 16 patients (11 and 5 from groups 1 and 2, respectively) and with the presentation of symptoms, such as mild dyspnea and chest discomfort, in 4 patients (1 and 3 from groups 1 and 2, respectively).

CONCLUSIONS

Measuring SpO using a pulse oximeter until POD2 was an effective method for early diagnosis of PE after TKA. No case of morbidity or mortality was observed after early diagnosis with early stage CTPA and management of PE. We recommend measuring SpO with a pulse oximeter for early diagnosing of PE in TKA.

摘要

引言

肺栓塞(PE)的早期诊断和积极治疗对于预防全膝关节置换术(TKA)后的严重并发症至关重要。本研究旨在探讨使用脉搏血氧仪测量血氧饱和度(SpO)对全膝关节置换术(TKA)后肺栓塞进行早期诊断的有效性。

材料与方法

我们连续检查了2015年1月至2019年11月期间接受TKA的1645例患者。术后用脉搏血氧仪测量SpO,若SpO在术后第2天(POD2)前维持在≥95%,则停止测量。为诊断PE,针对特定指征进行计算机断层扫描肺动脉造影(CTPA),包括持续低SpO<95%(第1组)、SpO突然下降(第2组)以及POD3后SpO下降并伴有症状(第3组)。此外,我们将患者分为单侧、同期和序贯TKA组,并采用特定统计技术比较结果。

结果

在1645例接受TKA的患者中,有20例发生PE(1.2%),仅4例出现症状性PE(0.24%)。58例(3.5%)患者进行了CTPA,其中20例被诊断为PE。在第1组(n = 34)、第2组(n = 21)和第3组(n = 3)中,分别在TKA后2.4、2.6和8.3天进行CTPA,诊断为PE的患者分别为12、8和0例。在782例单侧、416例同期和447例序贯(在同一住院期间间隔1或2周进行)TKA患者中,分别有38、18和2例接受CTPA,诊断为PE的患者分别为13、6和1例。所有诊断为PE的患者在POD2前均有持续低SpO<95%(第1组)或SpO2突然下降(第2组)。在诊断为PE的患者中,16例(第1组和第2组分别为11例和5例)SpO下降但无症状表现,4例(第1组和第2组分别为1例和3例)SpO下降并伴有轻度呼吸困难和胸部不适等症状。

结论

在POD2前使用脉搏血氧仪测量SpO是TKA后PE早期诊断的有效方法。早期通过CTPA诊断并对PE进行处理后,未观察到发病或死亡病例。我们建议在TKA中使用脉搏血氧仪测量SpO以早期诊断PE。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ce2/10801930/46d418414647/43019_2023_207_Fig1_HTML.jpg

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