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乳房切除术后血清肿形成:不同皮瓣固定技术的系统评价和网络荟萃分析。

Seroma formation after mastectomy: A systematic review and network meta-analysis of different flap fixation techniques.

机构信息

Department of Surgery, Zuyderland Medical Centre, Sittard-Geleen, The Netherlands.

Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, The Netherlands.

出版信息

J Surg Oncol. 2024 May;129(6):1015-1024. doi: 10.1002/jso.27589. Epub 2024 Jan 21.

DOI:10.1002/jso.27589
PMID:38247263
Abstract

Flap fixation is the most promising solution to prevent seroma formation after mastectomy. In this systematic review with network meta-analysis (NMA), three different techniques were compared. The NMA included 25 articles, comprising 3423 patients, and revealed that sutures are superior to tissue glue in preventing clinically significant seroma. In addition, running sutures seemed to be superior to interrupted sutures. An RCT comparing these suture techniques seems necessary, given the quality and nature of existing literature.

摘要

皮瓣固定是预防乳房切除术后血清肿形成的最有前途的解决方案。在这项系统评价的网络荟萃分析(NMA)中,比较了三种不同的技术。NMA 包括 25 篇文章,共 3423 例患者,结果表明缝线在预防临床上显著的血清肿方面优于组织胶。此外,连续缝线似乎优于间断缝线。鉴于现有文献的质量和性质,有必要进行一项比较这些缝线技术的 RCT。

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