Hojsak Iva, Kolaček Sanja
Department of Pediatrics, Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital, Zagreb, Croatia.
Department of Pediatrics, University of Zagreb School of Medicine, Zagreb, Croatia.
Pediatr Gastroenterol Hepatol Nutr. 2024 Jan;27(1):1-14. doi: 10.5223/pghn.2024.27.1.1. Epub 2024 Jan 9.
Probiotics are live microorganisms that confer health benefits to the host when administered in adequate amounts. Although recommendations for probiotic use should be strain-specific, many systematic reviews, including recommendations from different societies, recommend probiotic use in general, providing no relevant information for healthcare professionals regarding which probiotic to recommend for which clinical indication, at what dose, and for how long. This narrative review aimed to present the available evidence on the use of probiotics in the prevention and treatment of common gastrointestinal diseases in children, considering the strain and dose used. Furthermore, this study summarizes the evidence on the possible side effects and quality of products containing probiotics.
益生菌是一类活的微生物，当给予足够数量时，能给宿主带来健康益处。尽管益生菌的使用建议应具有菌株特异性，但许多系统评价，包括不同学会的建议，总体上都推荐使用益生菌，却未向医疗保健专业人员提供关于针对何种临床适应症推荐使用哪种益生菌、使用何种剂量以及使用多长时间的相关信息。本叙述性综述旨在介绍关于益生菌用于预防和治疗儿童常见胃肠道疾病的现有证据，同时考虑所使用的菌株和剂量。此外，本研究总结了关于含益生菌产品可能的副作用及质量的证据。
