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益生菌在儿童常见胃肠道疾病治疗与预防中的作用

Role of Probiotics in the Treatment and Prevention of Common Gastrointestinal Conditions in Children.

作者信息

Hojsak Iva, Kolaček Sanja

机构信息

Department of Pediatrics, Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital, Zagreb, Croatia.

Department of Pediatrics, University of Zagreb School of Medicine, Zagreb, Croatia.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2024 Jan;27(1):1-14. doi: 10.5223/pghn.2024.27.1.1. Epub 2024 Jan 9.

Abstract

Probiotics are live microorganisms that confer health benefits to the host when administered in adequate amounts. Although recommendations for probiotic use should be strain-specific, many systematic reviews, including recommendations from different societies, recommend probiotic use in general, providing no relevant information for healthcare professionals regarding which probiotic to recommend for which clinical indication, at what dose, and for how long. This narrative review aimed to present the available evidence on the use of probiotics in the prevention and treatment of common gastrointestinal diseases in children, considering the strain and dose used. Furthermore, this study summarizes the evidence on the possible side effects and quality of products containing probiotics.

摘要

益生菌是一类活的微生物,当给予足够数量时,能给宿主带来健康益处。尽管益生菌的使用建议应具有菌株特异性,但许多系统评价,包括不同学会的建议,总体上都推荐使用益生菌,却未向医疗保健专业人员提供关于针对何种临床适应症推荐使用哪种益生菌、使用何种剂量以及使用多长时间的相关信息。本叙述性综述旨在介绍关于益生菌用于预防和治疗儿童常见胃肠道疾病的现有证据,同时考虑所使用的菌株和剂量。此外,本研究总结了关于含益生菌产品可能的副作用及质量的证据。

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本文引用的文献

1
Probiotics for management of functional abdominal pain disorders in children.益生菌治疗儿童功能性腹痛疾病。
Cochrane Database Syst Rev. 2023 Feb 17;2(2):CD012849. doi: 10.1002/14651858.CD012849.pub2.
2
Strain-Specificity of Probiotics in Pediatrics: A Rapid Review of the Clinical Evidence.儿科益生菌的菌株特异性:临床证据的快速回顾
J Pediatr Gastroenterol Nutr. 2023 Feb 1;76(2):227-231. doi: 10.1097/MPG.0000000000003675. Epub 2022 Dec 1.
4
Treatment of Pediatric Infection.小儿感染的治疗
Antibiotics (Basel). 2022 Jun 1;11(6):757. doi: 10.3390/antibiotics11060757.

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