Marčun Varda Nataša, Golob Jančič Sonja, Močnik Mirjam
Department of Paediatrics, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia.
Medical Faculty, University of Maribor, Taborska 8, 2000 Maribor, Slovenia.
Children (Basel). 2023 Dec 23;11(1):18. doi: 10.3390/children11010018.
(1) Background: Ultrasound elastography is a novel ultrasound technique for evaluating tissue elasticity. One of the key factors influencing the measurement in children is excess weight. This study aimed to evaluate the effect of body composition, namely, fat mass, on liver and kidney ultrasound elastography in paediatric patients. (2) Methods: 114 participants, in whom bioimpedance, along with liver and kidney ultrasound elastography, were performed, were included (37 patients with chronic kidney disease, 46 patients with hypertension, and 31 healthy subjects). (3) Results: Bioimpedance analysis showed a significant correlation between liver elastography parameters and the phase angle ( = 0.002), fat-free mass ( = 0.001), body cell mass ( = 0.001), total body water ( = 0.001), extracellular water ( = 0.006), and, to lesser extent, fat mass ( = 0.041). On the contrary, kidney elastography parameters strongly correlated only with fat mass ( < 0.001 for both kidneys). (4) Conclusions: Liver and kidney stiffness increased in overweight participants and showed significant correlation with fat mass, particularly in the case of kidney elastography.
(1) 背景：超声弹性成像技术是一种用于评估组织弹性的新型超声技术。影响儿童测量结果的关键因素之一是超重。本研究旨在评估身体成分（即脂肪量）对儿科患者肝脏和肾脏超声弹性成像的影响。(2) 方法：纳入114名参与者，对其进行生物电阻抗分析以及肝脏和肾脏超声弹性成像检查（37例慢性肾病患者、46例高血压患者和31名健康受试者）。(3) 结果：生物电阻抗分析显示，肝脏弹性成像参数与相位角（r = 0.002）、去脂体重（r = 0.001）、身体细胞质量（r = 0.001）、总体水（r = 0.001）、细胞外液（r = 0.006）以及在较小程度上与脂肪量（r = 0.041）之间存在显著相关性。相反，肾脏弹性成像参数仅与脂肪量密切相关（双肾均P < 0.001）。(4) 结论：超重参与者的肝脏和肾脏硬度增加，且与脂肪量显著相关，在肾脏弹性成像方面尤为明显。
