Yang Teng, Jin Yuqi, Neogi Arup
Department of Physics, University of North Texas, Denton, Texas76203, United States.
Department of Materials Science and Engineering,University of North Texas, Denton, Texas76207, United States.
ACS Omega. 2022 Dec 21;8(1):1319-1330. doi: 10.1021/acsomega.2c06750. eCollection 2023 Jan 10.
The development of ultrasonic imaging techniques is optimized using artificial tissue phantoms before the practical applications. However, due to the strong attenuation and dispersion, accumulated fatty tissues can significantly impact the resolution and even feasibility of certain ultrasonic imaging modalities. An appropriate characterization of the acoustic properties on fatty phantoms can help the community to overcome the limitations. Some of the existing methods heavily overestimate attenuation coefficients by including the reflection loss and dispersion effects. Hence, in this study, we use numerical simulation-based comparison between two major attenuation measurement configurations. We further pointed out the pulse dispersion in viscoelastic tissue phantoms by simulations, which barely attracted attention in the existing studies. Using the selected attenuation and dispersion testing methods that were selected from the numerical simulation, we experimentally characterized the acoustic properties of common fatty tissue phantoms and compared the acoustic properties with the natural porcine fatty tissue samples. Furthermore, we selected one of the tissue phantoms to construct ultrasound imaging samples with some biomasses. With the known attenuation and dispersion of the tissue phantom, we showed the clarity enhancement of ultrasound imaging by signal post-processing to weaken the attenuation and dispersion effects.
在实际应用之前,利用人工组织体模优化超声成像技术的发展。然而,由于强烈的衰减和散射,积累的脂肪组织会显著影响某些超声成像模式的分辨率甚至可行性。对脂肪体模的声学特性进行适当表征有助于该领域克服这些限制。一些现有方法通过纳入反射损耗和散射效应,严重高估了衰减系数。因此,在本研究中,我们使用基于数值模拟的两种主要衰减测量配置之间的比较。我们还通过模拟指出了粘弹性组织体模中的脉冲散射,这在现有研究中几乎未引起关注。使用从数值模拟中选择的选定衰减和散射测试方法,我们通过实验表征了常见脂肪组织体模的声学特性,并将声学特性与天然猪脂肪组织样本进行了比较。此外,我们选择了一种组织体模来构建具有一些生物量的超声成像样本。鉴于组织体模已知的衰减和散射,我们通过信号后处理展示了超声成像清晰度的提高,以减弱衰减和散射效应。