Department of Radiology, Institute of Medical Science, Gyeongsang National University School of Medicine, Jinju 52727, Republic of Korea.
Department of Radiology, Gyeongsang National University Changwon Hospital, Changwon 51472, Republic of Korea.
Medicina (Kaunas). 2023 Dec 30;60(1):79. doi: 10.3390/medicina60010079.
The appearance of sclerotic bone lesions in contrast-enhanced computed tomography (CT) scans is often a significant concern for the possible presence of metastatic disease, especially in individuals with a known history of cancer. Prior research has demonstrated that in cases where patients suffer from thrombosis in major veins like the superior vena cava or the brachiocephalic vein, vertebral venous congestion can create imaging patterns on CT scans that resemble sclerotic bone metastases. However, instances of such imaging findings in patients without any form of venous obstruction are not commonly reported. In this study, we present cases of pseudopathologic vertebral enhancement observed consistently following left-side contrast injections in cancer patients devoid of venous obstruction. We aim to discuss and propose a potential mechanism for this phenomenon, drawing attention to a less commonly recognized diagnostic consideration in oncological imaging.
在对比增强计算机断层扫描（CT）扫描中出现硬化性骨病变通常是转移性疾病存在的重要关注点，特别是在有已知癌症病史的个体中。先前的研究表明，在患有上腔静脉或头臂静脉等主要静脉血栓形成的情况下，椎静脉充血可在 CT 扫描上产生类似于硬化性骨转移的影像学模式。然而，在没有任何形式静脉阻塞的患者中，这种影像学发现的情况并不常见。在本研究中，我们介绍了在无静脉阻塞的癌症患者中，左侧对比剂注射后一致观察到的假病理椎体增强的病例。我们旨在讨论并提出这种现象的潜在机制，提请注意在肿瘤影像学中不太被认识到的诊断考虑因素。
