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抗菌性ZnO@CeO纳米晶体:控制食源性病原体的潜在材料。

Antibacterial ZnO@CeO nanocrystals: Prospective material for control of foodborne pathogens.

作者信息

Al-Ghamdi Abdulaziz Yahya

机构信息

Department of Biology, Faculty of Science, Al-Baha University, Albaha, Saudi Arabia.

出版信息

Food Sci Technol Int. 2025 Sep;31(6):554-565. doi: 10.1177/10820132231226258. Epub 2024 Jan 22.

Abstract

Foodborne microbial infections are leading cause of many deadly illnesses. As a result, there is an anticipated need for the development of innovative packaging materials with effective antibacterial potential. This article describes preparation and characterization of innovative ZnO@CeO nanocrystals through a facile hydrothermal method, as well as their outstanding antibacterial properties. The ZnO@CeO nanocrystals used were prepared using precursors zinc acetate and cerium nitrate at 180°C. Various sophisticated physicochemical parameters were used to assess nanocrystals. The antibacterial activity was examined using minimum inhibitory concentration technique against four major foodborne pathogenic bacteria, namely (Gram positive) and (Gram negative) at four distinct concentrations (0-400 µg/mL). The in vitro cell compatibility test was done on fibroblasts According to our findings, the lowest concentration of ZnO@CeO nanocrystals limiting development of tested strains is 100 µg/mL. Additionally, the results show that the combination of ZnO and CeO can be synergistic, resulting in ZnO@CeO nanocrystals with enhanced antibacterial activity. To summarize, unique ZnO@CeO nanocrystals with a high surface-to-volume ratio with outstanding antibacterial activity and no harmful impact to mouse fibroblasts were shaped. The ZnO@CeO can be utilized to competently suppress microbial growth spoiling the food and could be utilized as economical and efficient future packaging material for food industries.

摘要

食源性微生物感染是许多致命疾病的主要原因。因此,预计需要开发具有有效抗菌潜力的创新包装材料。本文描述了通过简便的水热法制备和表征创新的ZnO@CeO纳米晶体,以及它们出色的抗菌性能。所使用的ZnO@CeO纳米晶体是在180°C下使用醋酸锌和硝酸铈前驱体制备的。使用各种复杂的物理化学参数来评估纳米晶体。使用最低抑菌浓度技术针对四种主要的食源性病原体细菌,即(革兰氏阳性)和(革兰氏阴性)在四个不同浓度(0-400μg/mL)下检测抗菌活性。在成纤维细胞上进行体外细胞相容性测试。根据我们的研究结果,限制受试菌株生长的ZnO@CeO纳米晶体的最低浓度为100μg/mL。此外,结果表明ZnO和CeO的组合可以具有协同作用,从而产生具有增强抗菌活性的ZnO@CeO纳米晶体。总之,形成了具有高表面积与体积比、出色抗菌活性且对小鼠成纤维细胞无有害影响的独特ZnO@CeO纳米晶体。ZnO@CeO可用于有效抑制破坏食物的微生物生长,并可作为食品工业未来经济高效的包装材料。

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