Ivanuta Marius, Puia Dragos, Pricop Catalin
Urology, "C.I. Parhon" Clinical Hospital, Iasi, ROU.
Urology, University for Medicine and Pharmacy "Grigore T. Popa", Iasi, ROU.
Cureus. 2023 Dec 23;15(12):e50980. doi: 10.7759/cureus.50980. eCollection 2023 Dec.
Benign prostatic hyperplasia (BPH) is a progressive disease that causes low urinary tract symptoms (LUTS). As prostatic volume grows, the prostatic urethra may become completely obstructed, resulting in full urine retention and acute hypogastric pain. Our research aimed to identify the optimal trial without catheter (TWOC) therapeutic approach and identify those factors that are associated with the recurrence of complete urinary retention (CUR).
The study enrolled with complete urinary retention and BPH were included in the study, after the insertion of a Foley catheter. The patients received tamsulosin 0.4 mg/day as an alpha-blocker treatment. In our investigation, patients who encountered complete urinary retention were randomly categorized into four groups based on the duration of urinary catheterization as determined by the attending urologist.
Maintaining the urethrovesical catheter for three to seven days was related to the highest success of spontaneous urination, which was statistically significant compared to other study groups. (p=0.0007). Age over 70 years, no alpha-blocker before the urinary retention episode, and prostatic volume exceeding 50 ml were all associated with decreased TWOC efficacy. We found the highest rates of spontaneous urination were after three to seven days of urinary catheterization.
BPH and complete urine retention can be managed by TWOC in many cases. Several factors affect the test's efficacy. Prolonged urinary catheter maintenance over seven days, prostatic volume over 50 ml, and age over 70 years are poor prognostic indicators.
良性前列腺增生(BPH)是一种导致下尿路症状(LUTS)的进行性疾病。随着前列腺体积增大,前列腺尿道可能会完全梗阻,导致完全尿潴留和急性下腹痛。我们的研究旨在确定最佳的无导尿管试验(TWOC)治疗方法,并确定与完全尿潴留(CUR)复发相关的因素。
本研究纳入了因BPH导致完全尿潴留且已插入Foley导尿管的患者。患者接受每日0.4mg坦索罗辛作为α受体阻滞剂治疗。在我们的调查中,根据主治泌尿科医生确定的导尿持续时间,将出现完全尿潴留的患者随机分为四组。
将尿道膀胱导尿管留置三到七天与自发排尿成功率最高相关,与其他研究组相比具有统计学意义(p = 0.0007)。70岁以上、尿潴留发作前未使用α受体阻滞剂以及前列腺体积超过50ml均与TWOC疗效降低相关。我们发现导尿三到七天后自发排尿率最高。
在许多情况下,BPH和完全尿潴留可以通过TWOC进行处理。有几个因素会影响该试验的疗效。导尿管留置时间超过七天、前列腺体积超过50ml以及年龄超过70岁都是预后不良的指标。