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良性前列腺增生急性尿潴留后无导尿管成功试验的预测因素:单中心多变量分析

Predictors of successful trial without catheter following acute urinary retention in benign prostatic enlargement: A single centre, multivariate analysis.

作者信息

Bansal Ankur, Arora Aditi

机构信息

Janak Surgicare Centre, Patiala, Punjab, India.

出版信息

Neurourol Urodyn. 2017 Sep;36(7):1757-1762. doi: 10.1002/nau.23194. Epub 2017 Jan 19.

DOI:10.1002/nau.23194
PMID:28101889
Abstract

OBJECTIVE

To evaluate the parameters which predict the success or failure of trial without catheter (TWOC) for acute urine retention (AUR).

MATERIALS AND METHODS

Medical records of 2 188 patients presenting with first episode of AUR were analyzed. All patients underwent catheterization and were started on α-blocker followed by TWOC. Age, baseline American urological association (AUA) score, prostate volume (PV), residual volume of urine (RV) and intravesical prostatic protrusion (IPP), prostate specific antigen (PSA) were recorded.

RESULTS

TWOC was successful in 737 patients (33.7%) and failed in 1 451 patients (66.3%). Patients with successful TWOC had lower mean age, PV, IPP, RV, AUA score, and PSA than those with failed TWOC. On multivariate analysis, the significant independent predictors were IPP, age, AUA score, PV, and RV at odds ratios of 3.11, 1.84, 1.78, 1.53, and 1.23, respectively. From ROC curve, IPP had cut off value of 9 mm and detected success of TWOC with sensitivity (S) of 91% and failure with specificity (s) of 90%. Similarly, cut off value of 64 years for age (S:86%, s:87%), 20 for AUA symptom score (S:83%, s:81%), 56 cc for PV (S:80%, s:74%) and 750 mL for RV (S:71%, s:68%) were obtained.

CONCLUSION

Age, baseline AUA score, IPP, PV, and RV independently predict the outcome of TWOC. Patients with IPP > 9 mm, age > 65 years, baseline AUA score > 20, PV > 56 cc, or RV > 750 mL have less probability of successful TWOC in AUR and can be considered for immediate surgery following an episode of AUR.

摘要

目的

评估预测急性尿潴留(AUR)无导尿管试验(TWOC)成败的参数。

材料与方法

分析2188例首次发生AUR患者的病历。所有患者均接受导尿,并开始使用α受体阻滞剂,随后进行TWOC。记录年龄、基线美国泌尿外科学会(AUA)评分、前列腺体积(PV)、残余尿量(RV)和膀胱内前列腺突出(IPP)、前列腺特异性抗原(PSA)。

结果

737例患者(33.7%)TWOC成功,1451例患者(66.3%)失败。TWOC成功的患者平均年龄、PV、IPP、RV、AUA评分和PSA均低于TWOC失败的患者。多因素分析显示,显著的独立预测因素为IPP、年龄、AUA评分、PV和RV,比值比分别为3.11、1.84、1.78、1.53和1.23。根据ROC曲线,IPP的截断值为9mm,检测TWOC成功的灵敏度(S)为91%,检测失败的特异度(s)为90%。同样,年龄的截断值为64岁(S:86%,s:87%),AUA症状评分为20(S:83%,s:81%),PV为56cc(S:80%,s:74%),RV为750mL(S:71%,s:68%)。

结论

年龄、基线AUA评分、IPP、PV和RV可独立预测TWOC的结果。IPP>9mm、年龄>65岁、基线AUA评分>20、PV>56cc或RV>750mL的AUR患者TWOC成功的可能性较小,AUR发作后可考虑立即手术。

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