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2020-22 年新冠大流行期间挪威和瑞典的死亡率:一项比较研究。

Mortality in Norway and Sweden during the COVID-19 pandemic 2020-22: A comparative study.

机构信息

Norwegian Institute of Public Health, Division of Mental and Physical Health Oslo, Norway.

Mälardalens University, Social Statistics and Analysis Population and Living Conditions, Statistics Sweden, Solna, Sweden; Public Health Agency of Sweden, Solna, Sweden.

出版信息

J Infect Public Health. 2024 Apr;17(4):719-726. doi: 10.1016/j.jiph.2023.10.033. Epub 2023 Nov 3.

Abstract

BACKGROUND

Norway and Sweden picked two different ways to mitigate the dissemination of the SARS-CoV-2 virus. Norway introduced the strictest lockdown in Europe with strict border controls and intense virus tracking of all local outbreaks while Sweden did not. That resulted in 477 COVID-19 deaths (Norway) and 9737 (Sweden) in 2020, respectively.

METHODS

Weekly number of COVID-19 related deaths and total deaths for 2020-22 were collected as well as weekly number of deaths for 2015-19 which were used as controls when calculating excess mortality. During the first 12-18 months with high rate of virus transmission in the society, excess mortality rates were used as substitute for COVID-19 deaths. When excess mortality rates later turned negative because of mortality displacement, COVID-19 deaths adjusted for bias due to overreporting were used.

RESULTS

There were 17521 COVID-19 deaths in Sweden and 4272 in Norway in the study period. The rate ratio (RR) of COVID-19 related deaths in Sweden vs. Norway to the end of week 43, 2022, was 2.11 (95% CI 2.05-2.19). RR of COVID-19 related deaths vs. excess number of deaths were 2.5 (Sweden) and 1.3 (Norway), respectively. RR of COVID-19 deaths in Sweden vs. Norway after adjusting for mortality displacement and lockdown, was 1.35 (95% CI 1.31-1.39), corresponding to saving 2025 life in Norway. If including all deaths in 2022, RR= 1.28 (95% CI 1.24-1.31).

CONCLUSIONS

Both COVID-19 related mortality and excess mortality rates are biased estimates. When adjusting for bias, mortality differences declined over time to about 30% higher mortality in Sweden after 30 months with pandemics.

摘要

背景

挪威和瑞典选择了两种不同的方式来减轻 SARS-CoV-2 病毒的传播。挪威实施了欧洲最严格的封锁措施,严格控制边境,并对所有本地疫情进行了密集的病毒追踪,而瑞典则没有。这导致 2020 年挪威 COVID-19 死亡人数为 477 人,瑞典为 9737 人。

方法

收集了 2020-22 年每周与 COVID-19 相关的死亡人数和总死亡人数,以及 2015-19 年每周的死亡人数,用作计算超额死亡率的对照。在社会上病毒传播率较高的最初 12-18 个月,超额死亡率被用作 COVID-19 死亡人数的替代指标。当超额死亡率后来因死亡率转移而变为负值时,使用因过度报告而调整后的 COVID-19 死亡人数。

结果

研究期间,瑞典有 17521 例 COVID-19 死亡,挪威有 4272 例。截至 2022 年第 43 周结束时,瑞典与挪威 COVID-19 相关死亡人数的比率(RR)为 2.11(95%CI 2.05-2.19)。与超额死亡人数相比,瑞典 COVID-19 相关死亡人数的 RR 为 2.5,挪威为 1.3。调整死亡率转移和封锁因素后,瑞典 COVID-19 死亡人数与挪威的 RR 为 1.35(95%CI 1.31-1.39),相当于在挪威挽救了 2025 条生命。如果包括 2022 年的所有死亡人数,RR=1.28(95%CI 1.24-1.31)。

结论

COVID-19 相关死亡率和超额死亡率都是有偏差的估计。当调整偏差时,死亡率差异随着时间的推移逐渐下降,在大流行 30 个月后,瑞典的死亡率高出约 30%。

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