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HIV drug resistance to integrase inhibitors in low- and middle-income countries.

作者信息

Fokam Joseph, Inzaule Seth, Colizzi Vittorio, Perno Carlo-Federico, Kaseya Jean, Ndembi Nicaise

机构信息

Chantal BIYA International Reference Centre for research on HIV/AIDS prevention and management, Yaoundé, Cameroon.

Faculty of Health Sciences, University of Buea, Buea, Cameroon.

出版信息

Nat Med. 2024 Mar;30(3):618-619. doi: 10.1038/s41591-023-02763-0.

DOI:10.1038/s41591-023-02763-0
PMID:38263265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11586446/
Abstract
摘要

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Open Forum Infect Dis. 2024 Jul 1;11(7):ofae365. doi: 10.1093/ofid/ofae365. eCollection 2024 Jul.

本文引用的文献

1
HIV-1 drug resistance in people on dolutegravir-based antiretroviral therapy: a collaborative cohort analysis.基于多替拉韦的抗逆转录病毒治疗患者中的 HIV-1 耐药性：一项协作队列分析。
Lancet HIV. 2023 Nov;10(11):e733-e741. doi: 10.1016/S2352-3018(23)00228-X. Epub 2023 Oct 10.
2
Treatment Emergent Dolutegravir Resistance Mutations in Individuals Naïve to HIV-1 Integrase Inhibitors: A Rapid Scoping Review.初治人类免疫缺陷病毒 1 型整合酶抑制剂人群中出现的治疗中出现的多替拉韦耐药突变：快速范围界定综述。
Viruses. 2023 Sep 15;15(9):1932. doi: 10.3390/v15091932.
3
The G118R plus R263K Combination of Integrase Mutations Associated with Dolutegravir-Based Treatment Failure Reduces HIV-1 Replicative Capacity and Integration.G118R 加上 R263K 整合酶突变组合与基于多替拉韦的治疗失败相关，降低了 HIV-1 的复制能力和整合。
Antimicrob Agents Chemother. 2023 May 17;67(5):e0138622. doi: 10.1128/aac.01386-22. Epub 2023 Apr 18.
4
First case of Dolutegravir and Darunavir/r multi drug-resistant HIV-1 in Cameroon following exposure to Raltegravir: lessons and implications in the era of transition to Dolutegravir-based regimens.喀麦隆首例拉替拉韦暴露后多药物耐药 HIV-1 型病毒（达芦那韦/利托那韦）：在向基于多替拉韦方案过渡时代的经验与启示。
Antimicrob Resist Infect Control. 2020 Aug 26;9(1):143. doi: 10.1186/s13756-020-00799-2.
5
Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R.多替拉韦一线抗逆转录病毒治疗失败并出现携带R263K和G118R的病毒株
N Engl J Med. 2019 Aug 29;381(9):887-889. doi: 10.1056/NEJMc1806554.
6
Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research.多替拉韦用于中低收入国家的一线抗逆转录病毒治疗：实施和研究的不确定性和机遇。
Lancet HIV. 2018 Jul;5(7):e400-e404. doi: 10.1016/S2352-3018(18)30093-6. Epub 2018 Jun 5.
7
Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors.在改用多替拉韦单药治疗后，HIV-1整合酶中出现G118R突变，导致对整合酶抑制剂产生交叉耐药。
J Antimicrob Chemother. 2016 Jul;71(7):1948-53. doi: 10.1093/jac/dkw071. Epub 2016 Mar 29.