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埃塞俄比亚街头居民自我药疗的程度及预测因素:一项多中心研究。

The magnitude and predictors of self-medication amongst street dwellers in Ethiopia: a multicentre study.

作者信息

Zeleke Tirsit Ketsela, Alamirew Bekalu Dessie, Bazezew Zegaye Agmassie, Alemu Muluken Adela, Jara Abdisa Gemedi, Abebe Rahel Belete

机构信息

Department of Pharmacy, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Department of Pharmacy, College of Medicine and Health Sciences, Bahr Dar University, Bahr Dar, Ethiopia.

出版信息

Drugs Context. 2024 Jan 11;13. doi: 10.7573/dic.2023-7-2. eCollection 2024.

Abstract

BACKGROUND

Low levels of living standards amongst street dwellers worldwide limit their access to conventional healthcare services, resulting in self-medication use for the treatment of an illness. Nevertheless, self-medication use has risks, including adverse drug reactions, increased polypharmacy, drug resistance, drug dependence, drug interactions and incorrect diagnosis. Ethiopia has a large street-dwelling community; however, there are no studies conducted in Ethiopia assessing self-medication use amongst street dwellers. This study provides insight into self-medication use and predictors amongst street dwellers in Ethiopia.

METHODS

A community-based, multicentre cross- sectional study was conducted amongst street dwellers from 1 September 2022 to 1 February 2023 at community drug-retail outlets in the three major cities in the Amhara region of Ethiopia. The data were obtained using an interviewer-administered questionnaire. Frequencies and percentages of descriptive statistics were calculated. Bivariable and multivariable logistic regression analyses were employed to indicate predictors of self-medication use. To determine statistical significance, a 95% confidence interval with a value below 0.05 was utilized.

RESULTS

The prevalence of self-medication use was 67.4%. Time and financial savings were reported as the reasons for most self-medication use. The most commonly reported illnesses for which people sought self-medication were gastrointestinal diseases. Low monthly income (adjusted OR 3.72, 95% CI 2.34-5.91) and residing near sewage areas (adjusted OR 3.37, 95% CI 2.03-5.58) were significantly associated with self-medication use.

CONCLUSION

Street dwellers had a high rate of self- medication use. Residing near sewage areas and having a low level of income were factors in self-medication use. Gastrointestinal diseases, respiratory ailments and dermatological conditions were the most frequently reported complaints, whereas antimicrobials and anthelmintics were the most commonly used medications. We recommend that healthcare services enhance outreach programmes to the most vulnerable people, such as street dwellers, especially those with lower monthly incomes and who live near sewage areas, to reduce self-medication rates.

摘要

背景

世界各地街头居民的生活水平较低,限制了他们获得传统医疗服务的机会,导致他们自行用药治疗疾病。然而,自行用药存在风险,包括药物不良反应、多药联用增加、耐药性、药物依赖性、药物相互作用和诊断错误。埃塞俄比亚有大量街头居住社区;然而,埃塞俄比亚尚未开展评估街头居民自行用药情况的研究。本研究深入了解了埃塞俄比亚街头居民的自行用药情况及其预测因素。

方法

2022年9月1日至2023年2月1日,在埃塞俄比亚阿姆哈拉地区三个主要城市的社区药店,对街头居民开展了一项基于社区的多中心横断面研究。数据通过访谈式问卷收集。计算描述性统计的频率和百分比。采用双变量和多变量逻辑回归分析来表明自行用药的预测因素。为确定统计学显著性,使用了95%置信区间且P值低于0.05。

结果

自行用药的患病率为67.4%。节省时间和金钱被报告为大多数自行用药的原因。人们寻求自行用药治疗的最常见疾病是胃肠道疾病。月收入低(调整后比值比3.72,95%置信区间2.34 - 5.91)和居住在污水区域附近(调整后比值比3.37,95%置信区间2.03 - 5.58)与自行用药显著相关。

结论

街头居民自行用药率较高。居住在污水区域附近和收入水平低是自行用药的因素。胃肠道疾病、呼吸道疾病和皮肤病是最常报告的病症,而抗菌药物和驱虫药物是最常用的药物。我们建议医疗服务机构加强针对最弱势群体(如街头居民,特别是月收入较低且居住在污水区域附近的人)的外展项目,以降低自行用药率。

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