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肝移植后的感染——时间线、管理与预防

Infections After Liver Transplant -Timeline, Management and Prevention.

作者信息

Shinde Ajay S, Kapoor Dharmesh

机构信息

Consultant Gastroenterologist and Hepatologist, Yashoda Hospitals, Secunderabad, Telangana, India.

Consultant Hepatologist, Yashoda Hospitals, Secunderabad, Telangana, India.

出版信息

J Clin Exp Hepatol. 2024 May-Jun;14(3):101316. doi: 10.1016/j.jceh.2023.101316. Epub 2023 Dec 14.

Abstract

Liver transplantation (LT) is the standard treatment for end- stage liver disease. Patient and graft survival have improved significantly in the last three decades owing to improvement in surgical technique, better perioperative management and better immunosuppressive regimens. However, LT recipients are at increased risk of infections, particularly in the first year after transplantation. The risk of infection is directly proportional to immunosuppressive regimen and graft function. In this review, we will briefly discuss the timeline of infections after liver transplant, preventive strategies and management of infectious complications.

摘要

肝移植(LT)是终末期肝病的标准治疗方法。由于手术技术的改进、更好的围手术期管理以及更优的免疫抑制方案,在过去三十年中,患者和移植物的存活率有了显著提高。然而,肝移植受者发生感染的风险增加,尤其是在移植后的第一年。感染风险与免疫抑制方案和移植物功能直接相关。在本综述中,我们将简要讨论肝移植后感染的时间线、预防策略以及感染并发症的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7c3/10801311/ee8ddf579bdb/ga1.jpg

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