Rolak Stacey, Said Adnan, German Rita, Hayney Mary S, Caldera Freddy
Department of Internal Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
Department of Medicine, Division of Gastroenterology and Hepatology, School of Medicine & Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Gastroenterol Hepatol (N Y). 2022 Apr;18(4):196-206.
Patients with chronic liver disease (CLD) and liver transplant recipients are at increased risk for infections from vaccine-preventable diseases. Gastroenterologists and hepatologists should assess patient immunization history, and necessary vaccinations should be given as soon as possible. Vaccines demonstrate superior immunogenicity when given earlier in the course of liver disease and prior to transplant. This article summarizes recommendations from the Advisory Committee on Immunization Practices for vaccinations in patients with CLD and liver transplant recipients, and includes a discussion of the influenza, herpes zoster, hepatitis A, hepatitis B, pneumococcal, human papillomavirus, and COVID-19 vaccines.
慢性肝病(CLD)患者和肝移植受者感染疫苗可预防疾病的风险增加。胃肠病学家和肝病学家应评估患者的免疫接种史,并应尽快进行必要的疫苗接种。在肝病病程早期和移植前接种疫苗时,疫苗表现出更强的免疫原性。本文总结了免疫实践咨询委员会针对CLD患者和肝移植受者疫苗接种的建议,并讨论了流感、带状疱疹、甲型肝炎、乙型肝炎、肺炎球菌、人乳头瘤病毒和新冠病毒疫苗。