Smith Ryan A, Pease Tyler J, Chiu Anthony K, Shear Brian M, Sahlani Mario N, Ratanpal Amit S, Ye Ivan B, Thomson Alexandra E, Bivona Louis J, Jauregui Julio J, Crandall Kenneth M, Sansur Charles A, Cavanaugh Daniel L, Koh Eugene Y, Ludwig Steven C
Division of Spine Surgery, Department of Orthopaedics, University of Maryland Medical Center, Baltimore, MD, USA.
Division of Spine Surgery, Department of Neurosurgery, University of Maryland Medical Center, Baltimore, MD, USA.
Global Spine J. 2025 Mar;15(2):1166-1173. doi: 10.1177/21925682241228219. Epub 2024 Jan 24.
Prospective, single-center study.
To evaluate the clinical relevance of the validated intraoperative bleeding severity scale (VIBe) in thoracolumbar spine surgery.
Adult patients aged 18 through 88 undergoing elective decompression, instrumentation, and fusion of the thoracolumbar spine were prospectively enrolled after informed consent was provided and written consent was obtained. Validated intraoperative bleeding severity scores were recorded intraoperatively. Univariate analysis consisted of Student T-tests, Pearson's χ Tests, Fisher's Exact Tests, linear regression, and binary logistic regression. Multivariable regression was conducted to adjust for baseline characteristics and potential confounding variables.
A total of N = 121 patients were enrolled and included in the analysis. After adjusting for confounders, VIBe scores were correlated with an increased likelihood of intraoperative blood transfusion (β = 2.46, = .012), postoperative blood transfusion (β = 2.36, = .015), any transfusion (β = 2.49, < .001), total transfusion volume (β = 180.8, = .020), and estimated blood loss (EBL) (β = 409, < .001). Validated intraoperative bleeding severity scores had no significant association with length of hospital stay, 30-day readmission, 30-day reoperation, 30-day emergency department visit, change in pre- to post-op hemoglobin and hematocrit, total drain output, or length of surgery.
The VIBe scale is associated with perioperative transfusion rates and EBL in patients undergoing thoracolumbar spine surgery. Overall, the VIBe scale has clinically relevant meaning in spine surgery, and shows potential utility in clinical research.
Level II.
前瞻性单中心研究。
评估经过验证的术中出血严重程度量表(VIBe)在胸腰椎脊柱手术中的临床相关性。
在获得成年患者(年龄18至88岁)知情同意并签署书面同意书后,前瞻性纳入接受胸腰椎脊柱择期减压、内固定和融合手术的患者。术中记录经过验证的术中出血严重程度评分。单因素分析包括Student T检验、Pearson卡方检验、Fisher精确检验、线性回归和二元逻辑回归。进行多变量回归以调整基线特征和潜在混杂变量。
总共纳入N = 121例患者并纳入分析。在调整混杂因素后,VIBe评分与术中输血可能性增加(β = 2.46,P = .012)、术后输血(β = 2.36,P = .015)、任何输血(β = 2.49,P < .001)、总输血量(β = 180.8,P = .020)和估计失血量(EBL)(β = 409,P < .001)相关。经过验证的术中出血严重程度评分与住院时间、30天再入院、30天再次手术、30天急诊就诊、术前至术后血红蛋白和血细胞比容变化、总引流量或手术时间无显著关联。
VIBe量表与胸腰椎脊柱手术患者的围手术期输血率和EBL相关。总体而言,VIBe量表在脊柱手术中具有临床相关意义,并在临床研究中显示出潜在效用。
二级。