Transfusion Department, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, P.R. China.
Transfus Apher Sci. 2021 Dec;60(6):103277. doi: 10.1016/j.transci.2021.103277. Epub 2021 Sep 21.
The goal of this study was to predict the probability of transfusion of red blood cells and the volume of blood consumption based on the clinical characteristics of patients before surgery.
The medical records of 565 patients over 65 years old who underwent posterior lumbar surgery and 586 patients over 65 years old receiving femoral fracture surgery were reviewed. The clinical characteristics of the patients were subjected to multivariate regression analysis. The scores of these factors' influences on intraoperative red blood cells infusion were based on the odds ratio of each multivariate risk factor. Non-linear regression was performed to predict the probability of intraoperative blood transfusion and the volume of blood used for patients with different scores.
The factors that significantly influenced blood use during lumbar spinal stenosis and femoral fracture surgery in aged patients(P < 0.05) included age, body mass index, abnormal coagulation function, preoperative hemoglobin, administration of antithrombotic drugs, multisegmental lesions of the lumbar spine, femoral shaft fracture, secondary lumbar surgery and the time from fracture to surgery exceeding 48 h. According to our risk scoring system, patients of posterior lumbar surgery scored 0-10 and patients of femoral fracture had a score of 0-12. More than 50 % of patients receiving an intraoperative red blood cells transfusion during surgery scored>1.
The scoring system can be used as a predictive model for the probability of red blood cells transfusion and the blood volume in aged patients undergoing lumbar spinal stenosis and femoral fracture surgeries.
本研究旨在根据患者术前的临床特征预测手术中红细胞输注的概率和血液消耗量。
回顾了 565 例 65 岁以上行后路腰椎手术和 586 例 65 岁以上行股骨骨折手术的患者的病历。对患者的临床特征进行多变量回归分析。根据每个多因素风险因素的优势比,对这些因素对术中红细胞输注影响的评分进行评分。对不同评分患者的术中输血概率和用血量进行非线性回归预测。
年龄、体重指数、凝血功能异常、术前血红蛋白、抗血栓药物的使用、腰椎多节段病变、股骨干骨折、二次腰椎手术以及骨折至手术时间超过 48 小时是影响老年患者腰椎管狭窄和股骨骨折手术中用血的显著因素(P<0.05)。根据我们的风险评分系统,后路腰椎手术患者的评分为 0-10 分,股骨骨折患者的评分为 0-12 分。超过 50%术中输注红细胞的患者评分>1。
评分系统可作为预测老年患者腰椎管狭窄和股骨骨折手术中红细胞输注概率和血容量的预测模型。