Dinkar Anju, Singh Jitendra, Yadav Mahima
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Infect Disord Drug Targets. 2024;24(5):e220124225941. doi: 10.2174/0118715265256882231128074609.
Leptospirosis is the most common zoonotic illness worldwide, caused by pathogenic spirochete bacteria called . It is clinically presented with mild to moderate in most cases. However, sometimes, the course may be severe with multiorgan dysfunction.
We present two rare cases of with peripheral dry gangrene of the lower extremities. A 25-year-old male, farmer by occupation without any significant past medical history had been diagnosed with a case of that complicated to digital gangrene on 15 days of illness during hospitalization. Another 21-year-old male student was admitted for leptospirosis and developed digital gangrene on 19 days of illness. All clinical findings were resolved on the steroid.
Apart from a high index of suspicion and awareness of unusual manifestations, serology plays a vital role in making an accurate and quick diagnosis to initiate appropriate therapy.
钩端螺旋体病是全球最常见的人畜共患病，由致病性螺旋体细菌引起。大多数情况下临床表现为轻至中度。然而，有时病程可能严重，伴有多器官功能障碍。
我们报告两例罕见的伴有下肢外周干性坏疽的钩端螺旋体病病例。一名25岁男性，职业为农民，既往无重大病史，在住院期间患病15天时被诊断为钩端螺旋体病并发指端坏疽。另一名21岁男性学生因钩端螺旋体病入院，在患病19天时出现指端坏疽。所有临床症状在使用类固醇后均得到缓解。
除了高度怀疑和认识到不寻常表现外，血清学在做出准确快速诊断以启动适当治疗方面起着至关重要的作用。
