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尼日利亚中北部一家三级医疗机构就诊者中乙型和丙型肝炎病毒感染的血清流行率:一项回顾性研究。

Seroprevalence of Hepatitis B and C Virus Infections among Healthcare Seekers at a Tertiary Health Facility in North-Central Nigeria: A Retrospective Study.

机构信息

Department of Chemical Pathology, Bingham University/Bingham University Teaching Hospital, Jos, Nigeria.

Department of Family Medicine, Bingham University/Bingham University Teaching Hospital, Jos, Nigeria. E-mail:

出版信息

West Afr J Med. 2023 Dec 30;40(12):1355-1361.

Abstract

BACKGROUND

Hepatitis B and C viral infections are among the common infectious diseases with global public health importance. Nigeria is among the countries identified to be hyper-endemic for hepatitis B virus (HBV) infection. This study aimed to determine the seroprevalence of HBV and hepatitis C virus (HCV) infections among healthcare seekers at Bingham University Teaching Hospital, Jos, Nigeria, to increase awareness among the populace and sensitize public health stakeholders.

METHODS

A retrospective study that involved data abstraction from the medical laboratory records of patients seeking care at Bingham University Teaching Hospital. The information collected included screening results for HBsAg and anti-HCV. Data were analyzed using SPSS version 24.

RESULTS

A total of 186 patients were screened for HBV infection and 96 were screened for HCV infection. The mean ages and standard deviations were 36.2 ± 15.05 years and 37.2 ± 14.48 years for those screened for HBV and HCV, respectively. The seroprevalence rate of HBV infection was 14.0% while the rate for HCV infection was 10.4%. Males had a higher HBV seroprevalence of 9.1% than females with 4.9%. For HCV seroprevalence, females recorded a higher prevalence of 6.2% compared to their male counterparts who had 4.2%. Among those screened for HBV, the young adult age group had the highest prevalence rate of 10.2%, while for the HCV screen the middle-aged group had the highest prevalence rate of 6.2%. These were, however, not statistically significant (p > 0.05).

CONCLUSION

This study has shown that both HBV and HCV infections are hyper-endemic. There is a need to intensify awareness campaigns and improve the implementation of preventive and management strategies for HBV and HCV infections.

摘要

背景

乙型肝炎和丙型肝炎病毒感染是具有全球公共卫生重要性的常见传染病之一。尼日利亚是被确定为乙型肝炎病毒(HBV)感染高度流行的国家之一。本研究旨在确定尼日利亚乔斯宾宁顿大学教学医院就诊者中乙型肝炎和丙型肝炎病毒(HCV)感染的血清流行率,以提高民众的认识,并使公共卫生利益相关者敏感化。

方法

这是一项回顾性研究,涉及从宾宁顿大学教学医院就诊患者的医学实验室记录中提取数据。收集的信息包括 HBsAg 和抗-HCV 的筛查结果。使用 SPSS 版本 24 进行数据分析。

结果

共筛查了 186 例乙型肝炎感染患者和 96 例丙型肝炎感染患者。分别筛查 HBV 和 HCV 的患者的平均年龄和标准差为 36.2 ± 15.05 岁和 37.2 ± 14.48 岁。HBV 感染的血清流行率为 14.0%,而 HCV 感染的血清流行率为 10.4%。男性的 HBV 血清流行率为 9.1%,高于女性的 4.9%。对于 HCV 血清流行率,女性的患病率为 6.2%,高于男性的 4.2%。在筛查 HBV 的人群中,年轻成年年龄组的患病率最高,为 10.2%,而在 HCV 筛查中,中年组的患病率最高,为 6.2%。然而,这些差异没有统计学意义(p > 0.05)。

结论

本研究表明,HBV 和 HCV 感染均高度流行。需要加强宣传活动,并改善 HBV 和 HCV 感染的预防和管理策略的实施。

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